Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 7/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17991467 | 0.85 | PDGFRB (0.38) | GRIN2BGRIN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14920915 | 0.76 | GRIN2B (0.40) | GRIN2BALDH1A1CYP2C9 | |
| SCHEMBL17713162 | 0.75 | KIF11 (0.38) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16540711 | 0.73 | PLAU (0.40) | GRIN2B | |
| SCHEMBL15999659 | 0.73 | NOS3 (0.33) | GRIN2B | |
| SCHEMBL14920301 | 0.73 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP3A4HPGDCYP2C19 | |
| SCHEMBL19190114 | 0.71 | — | — | |
| SCHEMBL16665036 | 0.70 | TP53 (0.45) | CYP1A2CYP3A4CYP2C9CYP2C19CHRNA7 | |
| SCHEMBL16771868 | 0.70 | CYP11B2 (0.50) | GRIN2BGRIN1PIK3CDCYP3A4CYP2C9 | |
| SCHEMBL19998622 | 0.69 | PDGFRB (0.44) | GRIN2BGRIN1MAP4K4ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9776967-B2 | Carboxamide derivatives as pesticidal compounds | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-03 | — | — | US | disclosed |
| US-9776967-B2 | Carboxamide derivatives as pesticidal compounds | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-03 | — | — | US | disclosed |
| US-9776967-B2 | Carboxamide derivatives as pesticidal compounds | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-03 | — | — | US | disclosed |
| EP-3057939-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | Bayer Animal Health GmbH (DE) | 2016-08-24 | — | — | EP | disclosed |
| US-20160221950-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-08-04 | — | — | US | disclosed |
| US-20160221950-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-08-04 | — | — | US | disclosed |
| US-20160221950-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-08-04 | — | — | US | disclosed |
| WO-2015055535-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2015-04-23 | — | — | WO | disclosed |
| WO-2015055535-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2015-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221950-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | ACHE, DDT, NIT2 | GRIN2B 391/4885GRIN1 721/4885GRM5 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.