Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MPI | P34949 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17711257 | 0.84 | KMT2A (0.49) | KMT2AMEN1ALDH1A1MAPTAPAF1 | |
| SCHEMBL3710953 | 0.80 | KMT2A (0.54) | KMT2AMEN1ALDH1A1MAPTAPAF1 | |
| SCHEMBL29456440 | 0.80 | KMT2A (0.54) | KMT2AMEN1ALDH1A1MAPTAPAF1 | |
| SCHEMBL17716642 | 0.79 | KDM4E (0.40) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL28804239 | 0.73 | KMT2A (0.54) | KMT2AMEN1ALDH1A1MAPTAPAF1 | |
| SCHEMBL11891548 | 0.73 | KMT2A (0.59) | KMT2AMEN1ALDH1A1MAPTAPAF1 | |
| SCHEMBL12228310 | 0.72 | KMT2A (0.49) | KMT2AMEN1ALDH1A1MAPTAPAF1 | |
| SCHEMBL3628380 | 0.70 | SLC40A1 (0.49) | KMT2AMEN1ALDH1A1MAPTAPAF1 | |
| SCHEMBL196848 | 0.70 | KMT2A (0.68) | KMT2AMEN1ALDH1A1MAPTAPAF1 | |
| SCHEMBL15634566 | 0.68 | KDM4E (0.56) | KMT2AMEN1ALDH1A1MAPTAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160122336-A1 | TRIFLUOROMETHYL ALCOHOLS AS MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (US) | 2016-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122336-A1 | TRIFLUOROMETHYL ALCOHOLS AS MODULATORS OF RORyt | RORC, RORA, RORB | KMT2A 1096/4885MEN1 4211/4885ALDH1A1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.