Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.32 |
| ▸ | CES1 | P23141 | 3/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118540 | 0.97 | TSHR (0.40) | TSHRDAONAPRTCA4CA14 | |
| SCHEMBL6669960 | 0.93 | TSHR (0.38) | TSHRDAONAPRTCA4CA14 | |
| SCHEMBL9622609 | 0.93 | TSHR (0.38) | TSHRDAONAPRTCA4CA14 | |
| SCHEMBL3481591 | 0.81 | ACHE (0.48) | TSHRTDP1ALDH1A1CES2CES1 | |
| SCHEMBL5596457 | 0.81 | ALDH1A1 (0.34) | TSHRDAONAPRTTDP1ALDH1A1 | |
| Phosphoric Acid SCHEMBL28124675 | 0.77 | CA2 (0.36) | TSHRDAONAPRTCA4CA2 | |
| SCHEMBL5596520 | 0.77 | TP53 (0.33) | TSHRALDH1A1CES2CES1PCSK9 | |
| SCHEMBL3481666 | 0.77 | ACHE (0.38) | TSHRALDH1A1CES2CES1LMNA | |
| SCHEMBL2783701 | 0.76 | — | — | |
| SCHEMBL3481968 | 0.75 | TP53 (0.54) | ALDH1A1KDM4ENPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006136-A1 | Solid-liquid phase interfacial polymerisation | DOW CORNING CORPORATION (US) | 2000-06-07 | — | — | EP | claimed |
| US-6046293-A | Solid-liquid phase interfacial polymerization | UNIVERSITY OF SOUTH AUSTRALIA (AU) | 2000-04-04 | — | — | US | claimed |
| US-7449536-B2 | Branched polymers from organohydrogensilicon compounds | DOW CORNING CORPORATION (US) | 2008-11-11 | — | — | US | disclosed |
| EP-1572779-B1 | BRANCHED POLYMERS FROM ORGANOHYDROGENSILICON COMPOUNDS | DOW CORNING (US) | 2008-05-21 | — | — | EP | disclosed |
| US-20060074212-A1 | Branched polymers from organohydrogensilicon compounds | DOW CORNING CORPORATION (US) | 2006-04-06 | — | — | US | disclosed |
| EP-1572779-A2 | BRANCHED POLYMERS FROM ORGANOHYDROGENSILICON COMPOUNDS | Dow Corning Corporation (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004058857-A2 | BRANCHED POLYMERS FROM ORGANOHYDROGENSILICON COMPOUNDS | DOW CORNING CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |
| EP-0799852-B1 | Preparation of polyorganosiloxanes by interfacial polymerization | DOW CORNING (US) | 2003-09-24 | — | — | EP | disclosed |
| EP-1138715-A1 | Organosilicon compositions from cyclosiloxanes | DOW CORNING CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| US-6294634-B1 | HEATING IN ABSENCE OF A SOLVENT A MIXTURE OF DIMETHYLCYCLOSILOXANE, CYCLOSILOXANE ANDCYCLOSILOXANE CONTAINING AN OXYALKYLENE SEGMENT, IN PRESENCE OF CATALYST TO CAUSE POLYMERIZATION | DOW CORNING CORPORATION | 2001-09-25 | — | — | US | disclosed |
| US-6207781-B1 | USING ALKALINE CATALYST; HEATING | DOW CORNING CORPORATION | 2001-03-27 | — | — | US | disclosed |
| EP-1069129-A2 | Organofunctional cocyclic siloxanes | DOW CORNING CORPORATION (US) | 2001-01-17 | — | — | EP | disclosed |
| US-6136938-A | TERPOLYMERIZATION OF AMINOALKYLSILOXANE POLYMER IN BASIC CATALYST PRESENCE | DOW CORNING CORPORATION (US) | 2000-10-24 | — | — | US | disclosed |
| EP-1035152-A1 | Silicone terpolymers containing dimethylsiloxane, higher ( =C8) alkylsiloxane and aminoalkylsiloxane groups | DOW CORNING CORPORATION (US) | 2000-09-13 | — | — | EP | disclosed |
| EP-1006136-A1 | Solid-liquid phase interfacial polymerisation | DOW CORNING CORPORATION (US) | 2000-06-07 | — | — | EP | disclosed |
| US-6046293-A | Solid-liquid phase interfacial polymerization | UNIVERSITY OF SOUTH AUSTRALIA (AU) | 2000-04-04 | — | — | US | disclosed |
| EP-0799851-A2 | Preparation of polyorganosilloxanes by interfacial polymerization | DOW CORNING CORPORATION (US) | 1997-10-08 | — | — | EP | disclosed |
| EP-0799852-A2 | Preparation of polyorganosiloxanes by interfacial polymerization | DOW CORNING CORPORATION (US) | 1997-10-08 | — | — | EP | disclosed |
| US-5637668-A | REACTING DIHALOSILOXANE COMPOUND AND ORGANOSILANOLATE AT INTERFACE OF TWO NONAQUEOUS SOLVENTS IMMISCIBLE IN EACH OTHER | DOW CORNING CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| US-5629401-A | Preparation of polyorganosiloxanes by interfacial polymerization | DOW CORNING CORPORATION (US) | 1997-05-13 | — | — | US | disclosed |