SCHEMBL17725307

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14557028	0.76	HSD11B1 (0.34)	DRD2
	SCHEMBL18452716	0.73	HSD11B1 (0.36)	DRD2
	SCHEMBL1544604	0.71	NPC1 (0.51)	—
	SCHEMBL392717	0.71	HSD11B1 (0.53)	DRD2
	SCHEMBL1543914	0.69	SMN1; SMN2 (0.46)	—
	SCHEMBL14557023	0.69	LMNA (0.42)	DRD2
	SCHEMBL31286526	0.69	KCNH2 (0.38)	LRRK2PIM1KDRTEKKCNH2
	SCHEMBL19612589	0.69	HPGDS (0.39)	DRD2DRD3KCNH2
	SCHEMBL13049801	0.69	DRD2 (0.34)	DRD2DRD3KCNH2
	SCHEMBL28432597	0.68	MKNK1 (0.49)	BRD4LRRK2KDREPHB4TEK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.