Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Sulfoxide SCHEMBL8483068 | 1.00 | — | — | |
| Dimethyl Sulfoxide SCHEMBL6082696 | 0.88 | ALDH1A1 (0.39) | — | |
| Dimethyl Sulfoxide SCHEMBL9877938 | 0.85 | PPIP5K2 (0.31) | — | |
| SCHEMBL28021775 | 0.84 | — | — | |
| Ethane SCHEMBL23013321 | 0.83 | CES2 (0.33) | — | |
| Methyl Alcohol SCHEMBL7718124 | 0.83 | CA2 (0.32) | — | |
| Chloromethane SCHEMBL28080031 | 0.83 | CA2 (0.32) | — | |
| SCHEMBL27623481 | 0.83 | CA2 (0.35) | — | |
| SCHEMBL52 | 0.83 | CA2 (0.35) | — | |
| Hydrochloric Acid SCHEMBL8958370 | 0.80 | CA2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462724-A | Preparation method of tulathromycin intermediate epoxide | 新发药业有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-113666978-A | Preparation method of macrolide compound and intermediate used by same | 洛阳惠中兽药有限公司 | 2021-11-19 | — | — | CN | claimed |
| CN-109678811-B | Asymmetric preparation method of florfenicol intermediate cyclic compound | 湖北中牧安达药业有限公司 | 2020-12-29 | — | — | CN | claimed |
| CN-109678811-A | A kind of asymmetric preparation method of florfenicol intermediate cyclic product | 湖北中牧安达药业有限公司 | 2019-04-26 | — | — | CN | claimed |
| CN-102786569-B | The preparation method of Tulathromycin intermediate and preparation method thereof and Tulathromycin | 安徽中升药业有限公司 | 2016-12-07 | — | — | CN | claimed |
| CN-102260306-B | Novel method for preparing tulathromycin | SHANDONG LUKANG SHELILE PHARMACEUTICAL CO LTD | 2012-07-18 | — | — | CN | claimed |
| CN-102260306-A | Novel method for preparing tulathromycin | — | 2011-11-30 | — | — | CN | claimed |
| EP-1327637-B1 | Process for the preparation of L-Ribose | UNIV GEORGIA RES FOUND (US) | 2005-09-14 | — | — | EP | claimed |
| US-6894159-B2 | Process for the preparation of 2′-fluoro-5-methyl-beta-L-arabino-furanosyluridine | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION (US) | 2005-05-17 | — | — | US | claimed |
| US-20030139593-A1 | Process for the preparation of 2'-fluoro-5-methyl-beta-L-arabino-furanosyluridine | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION INC. | 2003-07-24 | — | — | US | claimed |
| EP-1327637-A1 | Process for the preparation of L-Ribose | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2003-07-16 | — | — | EP | claimed |
| EP-0998482-B1 | PROCESS FOR THE PREPARATION OF 2'-FLUORO-5-METHYL-BETA-L-ARABINOFURANOSYLURIDINE | UNIV GEORGIA RES FOUND (US) | 2003-04-02 | — | — | EP | claimed |
| US-6512107-B2 | Generating preferential uridine derivative | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION | 2003-01-28 | — | — | US | claimed |
| US-20020062018-A1 | PROCESS FOR THE PREPARATION OF 2'- FLUORO-5-METHYL-BETA-L-ARABINO- FURANOSYLURIDINE | GEORGIA, UNIVERSITY OF, RESEARCH FOUNDATION INC., THE | 2002-05-23 | — | — | US | claimed |
| EP-0998482-A1 | PROCESS FOR THE PREPARATION OF 2'-FLUORO-5-METHYL-$g(b) -L-ARABINOFURANOSYLURIDINE | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2000-05-10 | — | — | EP | claimed |
| WO-1999005158-A1 | PROCESS FOR THE PREPARATION OF 2'-FLUORO-5-METHYL-β -L-ARABINOFURANOSYLURIDINE | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1999-02-04 | — | — | WO | claimed |
| WO-2023229032-A1 | THERAPEUTIC FOR CANCER REFRACTORY TO IMMUNE CHECKPOINT INHIBITOR | 住友ファーマ株式会社 | 2023-11-30 | — | — | WO | disclosed |
| EP-4253377-A1 | 5-HETEROARYL-1H-PYRAZOL-3-AMINE DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-10-04 | — | — | EP | disclosed |
| US-4180654-A | 4\"-Deoxy-4\"-acylamido derivatives of oleandomycin, erythromycin and erythromycin carbonate | PFIZER INC. (US) | 1979-12-25 | — | — | US | disclosed |
| US-4150220-A | Semi-synthetic 4\"-erythromycin A derivatives | PFIZER INC. (US) | 1979-04-17 | — | — | US | disclosed |