Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923752 | 1.00 | TSHR (0.64) | TSHRMAPK1MAPTHSD17B10ALDH1A1 | |
| Nitrobenzene SCHEMBL11647957 | 0.88 | ALDH1A1 (0.52) | TSHRMAPK1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL30976988 | 0.83 | TSHR (0.60) | TSHRMAPK1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL400340 | 0.83 | TSHR (0.60) | TSHRMAPK1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL10893772 | 0.82 | TSHR (0.48) | TSHRMAPK1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL7862606 | 0.81 | PDE7A (0.49) | TSHRMAPK1MAPTALDH1A1LMNA | |
| SCHEMBL11859872 | 0.81 | TSHR (0.47) | TSHRMAPK1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL27782473 | 0.81 | LMNA (0.51) | TSHRMAPK1MAPTALDH1A1LMNA | |
| SCHEMBL1524058 | 0.80 | MAPK1 (0.72) | TSHRMAPK1ALDH1A1LMNAPOLB | |
| Methyl Alcohol SCHEMBL28263562 | 0.80 | TSHR (0.56) | TSHRMAPK1MAPTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118403473-A | Gas-water separation membrane framework, normal pressure VOCs self-breathing gas proton separation membrane and application thereof | 辽宁东德恩环保科技有限公司 | 2024-07-30 | — | — | CN | claimed |
| CN-118067810-A | Bio-based polyimide humidity sensor and preparation and application thereof | 华南理工大学 | 2024-05-24 | — | — | CN | claimed |
| EP-1493061-A4 | POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION | BREWER SCIENCE INC (US) | 2009-01-07 | — | — | EP | claimed |
| US-7132219-B2 | Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition | BREWER SCIENCE INC. (US) | 2006-11-07 | — | — | US | claimed |
| CN-1195730-C | Process for producing nitrodiphenyl amines | BAYER AG (DE) | 2005-04-06 | — | — | CN | claimed |
| EP-1493061-A2 | POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION | Brewer Science, Inc. (US) | 2005-01-05 | — | — | EP | claimed |
| US-20030219541-A1 | Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition | BREWER SCIENCE, INC. | 2003-11-27 | — | — | US | claimed |
| WO-2003087233-A2 | POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION | BREWER SCIENCE, INC. (US) | 2003-10-23 | — | — | WO | claimed |
| US-6235937-B1 | Process for the preparation of nitrodiphenylamines | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | claimed |
| CN-1287116-A | Process for producing nitrodiphenyl amines | BAYER AG (DE) | 2001-03-14 | — | — | CN | claimed |
| US-20250114461-A1 | CDK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-04-10 | — | — | US | disclosed |
| US-12097261-B2 | CDK2 degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2024-09-24 | — | — | US | disclosed |
| US-20240262792-A1 | USP30 INHIBITORS AND USES THEREOF | VINCERE BIOSCIENCES, INC. | 2024-08-08 | — | — | US | disclosed |
| CN-118403473-A | Gas-water separation membrane framework, normal pressure VOCs self-breathing gas proton separation membrane and application thereof | 辽宁东德恩环保科技有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-118067810-A | Bio-based polyimide humidity sensor and preparation and application thereof | 华南理工大学 | 2024-05-24 | — | — | CN | disclosed |
| US-4059627-A | HYDROGENATION OF CHLORINATED NITRO AROMATIC, NOBLE METAL CATALYST, THIOETHER | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-22 | — | — | US | disclosed |
| US-4053481-A | CHOLESTEROL AND TRIGLYCERIDE LEVEL LOWERING PROPERTIES | G. D. SEARLE & CO. (US) | 1977-10-11 | — | — | US | disclosed |
| US-4013664-A | PSCHORR CYCLIZATION | RESEARCH CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |
| US-3976639-A | Intermediates for indoles | HOFFMANN-LA ROCHE INC. (US) | 1976-08-24 | — | — | US | disclosed |
| US-3966830-A | SILICA, ALUMINA | TEIJIN LIMITED (JA) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12097261-B2 | CDK2 degraders and uses thereof | CDK2, CDK20, CDK1 | TSHR 3442/4885MAPK1 1869/4885MAPT 2735/4885 |
| US-20250114461-A1 | CDK2 DEGRADERS AND USES THEREOF | CDK2, CDK20, CDK1 | TSHR 3442/4885MAPK1 1869/4885MAPT 2735/4885 |
| US-20240262792-A1 | USP30 INHIBITORS AND USES THEREOF | USP30, USP28, USP1 | TSHR 3997/4885MAPK1 2205/4885MAPT 2434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.