Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | SREBF2 | Q12772 | 2/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3174725 | 0.83 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2KDM4ESREBF2 | |
| SCHEMBL2615402 | 0.81 | GAA (0.65) | RAB9ANPC1SMN1; SMN2KDM4ESREBF2 | |
| SCHEMBL28679988 | 0.79 | LTA4H (0.66) | RAB9ANPC1SMN1; SMN2KDM4ELTA4H | |
| SCHEMBL3823252 | 0.79 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2KDM4ELTA4H | |
| SCHEMBL3761118 | 0.79 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL231094 | 0.79 | LTA4H (0.80) | RAB9ANPC1SMN1; SMN2KDM4ESREBF2 | |
| SCHEMBL28327240 | 0.79 | KDM4E (0.86) | RAB9ANPC1SMN1; SMN2KDM4ESREBF2 | |
| SCHEMBL28673241 | 0.79 | PTGS2 (0.50) | RAB9ANPC1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL28931077 | 0.79 | NPC1 (0.69) | RAB9ANPC1SMN1; SMN2KDM4ELTA4H | |
| SCHEMBL2225468 | 0.78 | ALDH1A1 (0.63) | RAB9ANPC1SMN1; SMN2KDM4ESREBF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912595-A | Compound containing thiazole or thiadiazole structure and application thereof | 中国药科大学 | 2022-01-11 | — | — | CN | disclosed |
| US-20110112103-A1 | 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112103-A1 | 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND | EPOR, CBR1, CBR3 | RAB9A 4018/4885NPC1 3977/4885SMN1; SMN2 2425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.