Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1775285 | 0.85 | GPR119 (0.47) | GPR119KDM4EMAPTTHRB | |
| SCHEMBL22262887 | 0.84 | GPR119 (0.52) | GPR119KDM4EMAPTTHRBPTPN2 | |
| SCHEMBL17541701 | 0.83 | GPR119 (0.52) | GPR119KDM4EMAPTTHRBPTPN2 | |
| SCHEMBL2068875 | 0.83 | BAZ2A (0.43) | KDM4E | |
| SCHEMBL27829485 | 0.82 | GPR119 (0.34) | GPR119 | |
| SCHEMBL14359823 | 0.82 | GPR119 (0.52) | GPR119KDM4EMAPTTHRBPTPN2 | |
| SCHEMBL3685040 | 0.81 | GPR119 (0.49) | GPR119KDM4EMAPTTHRBPTPN2 | |
| SCHEMBL1773538 | 0.81 | FAAH (0.37) | — | |
| SCHEMBL419123 | 0.81 | GPR119 (0.51) | GPR119KDM4EMAPTTHRBHPGD | |
| SCHEMBL28788513 | 0.81 | GPR119 (0.51) | GPR119KDM4EMAPTTHRBPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9603833-B2 | Benzene or thiophene derivative and use thereof as VAP-1 inhibitor | R-TECH UENO, LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-9603833-B2 | Benzene or thiophene derivative and use thereof as VAP-1 inhibitor | R-TECH UENO, LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-9603833-B2 | Benzene or thiophene derivative and use thereof as VAP-1 inhibitor | R-TECH UENO, LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| EP-2563786-B1 | Ketoheteroarylpiperidine and piperazine derivatives as fungicides | BAYER IP GMBH (DE) | 2016-11-02 | — | — | EP | disclosed |
| US-9357779-B2 | Ketoheteroarylpiperdine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-07 | — | — | US | disclosed |
| US-9220266-B2 | Ketoheteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-29 | — | — | US | disclosed |
| EP-2334669-B1 | HETEROCYCLYL-SUBSTITUTED THIAZOLES AS PLANT PROTECTION AGENTS | BAYER IP GMBH (DE) | 2015-12-23 | — | — | EP | disclosed |
| EP-2886534-A1 | Benzene or thiophene derivative and use thereof as VAP-1 inhibitor | R-Tech Ueno, Ltd. (JP) | 2015-06-24 | — | — | EP | disclosed |
| EP-2886534-A1 | Benzene or thiophene derivative and use thereof as VAP-1 inhibitor | R-Tech Ueno, Ltd. (JP) | 2015-06-24 | — | — | EP | disclosed |
| US-20150166525-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R TECH UENO LTD (JP) | 2015-06-18 | — | — | US | disclosed |
| CN-102971314-A | Ketoheteroarylpiperidine and ketoheteroarylpiperazine derivates as fungicides | BAYER CROPSCIENCE AG | 2013-03-13 | — | — | CN | disclosed |
| US-20110312999-A1 | Ketoheteroarylpiperidine and -Piperazine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-12-22 | — | — | US | disclosed |
| EP-2334669-A1 | HETEROCYCLYL-SUBSTITUTED THIAZOLES AS PLANT PROTECTION AGENTS | Bayer CropScience AG (DE) | 2011-06-22 | — | — | EP | disclosed |
| US-7943774-B2 | Heterocyclyl-substituted thiazoles as crop protection agents | BAYER CROPSCIENCE AG (DE) | 2011-05-17 | — | — | US | disclosed |
| US-20110059957-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2011-03-10 | — | — | US | disclosed |
| US-20110059957-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2011-03-10 | — | — | US | disclosed |
| US-20110059957-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2011-03-10 | — | — | US | disclosed |
| US-20100137245-A1 | Heteerocyclyl-substituted thiazoles as crop protection agents | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | US | disclosed |
| WO-2010037479-A1 | HETEROCYCLYL-SUBSTITUTED THIAZOLES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2010-04-08 | — | — | WO | disclosed |
| WO-2009145360-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166525-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | VAPB, VAPA, BET1 | GPR119 3327/4885KDM4E 1213/4885MAPT 1522/4885 |
| US-20110059957-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | VAPB, VAPA, BET1 | GPR119 3327/4885KDM4E 1213/4885MAPT 1522/4885 |
| US-20110312999-A1 | Ketoheteroarylpiperidine and -Piperazine Derivatives as Fungicides | CYP4Z1, CYP51A1, KCNH1 | GPR119 1043/4885KDM4E 68/4885MAPT 2478/4885 |
| US-20100137245-A1 | Heteerocyclyl-substituted thiazoles as crop protection agents | CYP8B1, CYP51A1, HPD | GPR119 3388/4885KDM4E 3603/4885MAPT 3632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.