Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1535594 | 0.85 | TSHR (0.54) | TSHRALDH1A1AOC3CARM1PRMT6 | |
| SCHEMBL294642 | 0.83 | TSHR (0.64) | TSHRALDH1A1AOC3CA2CARM1 | |
| SCHEMBL5462064 | 0.82 | TSHR (0.55) | TSHRALDH1A1AOC3CALM1CA2 | |
| SCHEMBL4397375 | 0.81 | GAA (0.44) | TSHRALDH1A1AOC3CA2MGLL | |
| SCHEMBL3374460 | 0.81 | TSHR (0.48) | TSHRALDH1A1AOC3CARM1PRMT6 | |
| SCHEMBL5943982 | 0.81 | HTT (0.46) | TSHRALDH1A1AOC3CARM1PRMT6 | |
| SCHEMBL10840009 | 0.78 | AOC3 (0.58) | TSHRALDH1A1AOC3CALM1CA2 | |
| SCHEMBL10842660 | 0.78 | TSHR (0.50) | TSHRALDH1A1AOC3CA2CYP2C19 | |
| SCHEMBL3371050 | 0.78 | TSHR (0.45) | TSHRALDH1A1AOC3OPRK1KCNH2 | |
| SCHEMBL7248276 | 0.76 | TSHR (0.50) | TSHRALDH1A1AOC3CALM1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943605-B2 | Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses | UCB PHARMA S.A. (BE) | 2011-05-17 | — | — | US | claimed |
| EP-1673349-B1 | BENZIMIDAZOLE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S BIO PTE LTD (SG) | 2010-06-30 | — | — | EP | claimed |
| US-20090023708-A1 | Compounds Comprising a Lactam or a Lactam Derivative Moiety, Processes for Making Them, and Their Uses | UCB PHARMA, S.A. (BE) | 2009-01-22 | — | — | US | claimed |
| CN-101296902-A | Compounds comprising lactam or lactam derivative moieties, processes for preparing them and their use | UCB PHARMA SA (BE) | 2008-10-29 | — | — | CN | claimed |
| EP-1943217-A1 | COMPOUNDS COMPRISING A LACTAM OR A LACTAM DERIVATIVE MOIETY, PROCESSES FOR MAKING THEM, AND THEIR USES | UCB Pharma, S.A. (BE) | 2008-07-16 | — | — | EP | claimed |
| EP-1673349-A4 | BENZIMIDAZOLE DERIVATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S BIO PTE LTD (SG) | 2008-01-23 | — | — | EP | claimed |
| WO-2007048595-A1 | COMPOUNDS COMPRISING A LACTAM OR A LACTAM DERIVATIVE MOIETY, PROCESSES FOR MAKING THEM, AND THEIR USES | UCB PHARMA, S.A. (BE) | 2007-05-03 | — | — | WO | claimed |
| JP-2007505942-A | — | — | 2007-03-15 | — | — | JP | claimed |
| US-20070043043-A1 | Benzimidazole derivates: preparation and pharmaceutical applications | S*BIO PTE LTD. (SG) | 2007-02-22 | — | — | US | claimed |
| EP-1673349-A1 | BENZIMIDAZOLE DERIVATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*Bio Pte Ltd (SG) | 2006-06-28 | — | — | EP | claimed |
| WO-2005028447-A1 | BENZIMIDAZOLE DERIVATES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2005-03-31 | — | — | WO | claimed |
| EP-1074544-B1 | Process for production of 3-(3-pyridyl)-1-propanol derivatives | KANEKA CORP (JP) | 2003-08-27 | — | — | EP | claimed |
| US-6586644-B2 | Reacting aldehyde compound and terminal acetylene in presence of optically active amino alcohol, using tertiary amine and zinc halogenated lower alkane sulfonate as catalyst | Carreira, Erick M. (CH) | 2003-07-01 | — | — | US | claimed |
| US-20030088100-A1 | Process for producing optically active propargyl alcohols | SUMIKA FINE CHEMICALS CO., LTD. | 2003-05-08 | — | — | US | claimed |
| EP-1095043-A1 | TRIOXANE DERIVATIVES | The Hong Kong University of Science & Technology (HK) | 2001-05-02 | — | — | EP | claimed |
| WO-2000004026-A1 | TRIOXANE DERIVATIVES | THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) | 2000-01-27 | — | — | WO | claimed |
| EP-3864002-B1 | ADDITION-FRAGMENTATION AGENT WITH PENDENT AMINE GROUPS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-12-27 | — | — | EP | disclosed |
| WO-2023101004-A1 | OLEFIN RESIN, METHOD FOR MANUFACTURING SAME, AND APPLICATION FOR SAME | 三井化学株式会社 | 2023-06-08 | — | — | WO | disclosed |
| US-4427753-A | Electrophotographic photosensitive member with disazo or trisazo compound | CANON KABUSHIKI KAISHA (JP) | 1984-01-24 | — | — | US | disclosed |
| US-4418133-A | Disazo photoconductive material and electrophotographic photosensitive member having disazo pigment layer | CANON KABUSHIKI KAISHA (JP) | 1983-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043043-A1 | Benzimidazole derivates: preparation and pharmaceutical applications | HDAC5, HDAC1, HDAC4 | TSHR 3393/4885ALDH1A1 305/4885AOC3 3191/4885 |
| US-20030088100-A1 | Process for producing optically active propargyl alcohols | ADH1A, ADH1C, ADH5 | TSHR 53/4885ALDH1A1 27/4885AOC3 59/4885 |
| US-20090023708-A1 | Compounds Comprising a Lactam or a Lactam Derivative Moiety, Processes for Making Them, and Their Uses | COASY, FURIN, PEPD | TSHR 4554/4885ALDH1A1 1149/4885AOC3 3344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.