Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1776018 | 0.81 | TSHR (0.55) | ALDH1A1TSHRPYCR1AOC3NPC1 | |
| SCHEMBL516674 | 0.80 | BCHE (0.49) | GAAALDH1A1TSHRPYCR1AOC3 | |
| SCHEMBL2688603 | 0.80 | BCHE (0.49) | GAAALDH1A1TSHRPYCR1AOC3 | |
| SCHEMBL4446654 | 0.78 | GAA (0.44) | GAAALDH1A1TSHRPYCR1AOC3 | |
| Hydrochloric Acid SCHEMBL10548138 | 0.78 | BCHE (0.48) | GAAALDH1A1TSHRPYCR1GRIN2D | |
| SCHEMBL11813538 | 0.78 | GAA (0.44) | GAAALDH1A1TSHRPYCR1AOC3 | |
| Hydrochloric Acid SCHEMBL3752186 | 0.78 | BCHE (0.48) | GAAALDH1A1TSHRPYCR1AOC3 | |
| SCHEMBL859510 | 0.77 | GAA (0.43) | GAAALDH1A1TSHRPYCR1AOC3 | |
| SCHEMBL4631652 | 0.77 | GAA (0.43) | GAAALDH1A1TSHRPYCR1AOC3 | |
| SCHEMBL4960734 | 0.77 | GAA (0.43) | GAAALDH1A1TSHRPYCR1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962919-B2 | Nitrogen-containing heterocyclic compounds, their production and use | TAKEDA PHARMACEUTICAL CO., LTD. (JP) | 2005-11-08 | — | — | US | claimed |
| EP-1042325-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2005-09-21 | — | — | EP | claimed |
| US-20020103210-A1 | Nitrogen-containing heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. | 2002-08-01 | — | — | US | claimed |
| US-6413972-B1 | 5,8-DIHYDRO-3-METHYL-5-OXO-8-(1-OXO-1-PHENYL-2-PROPYL)-2 -PHENYLIMIDAZO(1,2-A)PYRIMIDINE-6-CARBOXYLIC ACID ETHYL ESTER; GONADOTROPIN-RELEASING HORMONE ANTAGONIZING ACTIVITY; LOW TOXICITY; ANTICARCINOGENIC AGENT; CONTRACEPTIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | claimed |
| EP-1042325-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-10-11 | — | — | EP | claimed |
| WO-1999033831-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-08 | — | — | WO | claimed |
| US-20090048273-A1 | PREMATURE OVULATION PREVENTIVE AGENT | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-02-19 | — | — | US | disclosed |
| EP-1917978-A1 | PREMATURE OVULATION PREVENTIVE AGENT | Takeda Pharmaceutical Company Limited (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-20050250793-A1 | Preventives/remedies for hot flash | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-11-10 | — | — | US | disclosed |
| US-6962919-B2 | Nitrogen-containing heterocyclic compounds, their production and use | TAKEDA PHARMACEUTICAL CO., LTD. (JP) | 2005-11-08 | — | — | US | disclosed |
| EP-1042325-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2005-09-21 | — | — | EP | disclosed |
| EP-1495768-A1 | PREVENTIVES/REMEDIES FOR HOTFLASH | Takeda Pharmaceutical Company Limited (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-20040116522-A1 | Medicinal solutions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-17 | — | — | US | disclosed |
| EP-1374855-A1 | MEDICINAL SOLUTIONS | Takeda Chemical Industries, Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |
| US-20030134863-A1 | Preventives/remedies for alzheimer's disease | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2003-07-17 | — | — | US | disclosed |
| US-20020103210-A1 | Nitrogen-containing heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. | 2002-08-01 | — | — | US | disclosed |
| US-6413972-B1 | 5,8-DIHYDRO-3-METHYL-5-OXO-8-(1-OXO-1-PHENYL-2-PROPYL)-2 -PHENYLIMIDAZO(1,2-A)PYRIMIDINE-6-CARBOXYLIC ACID ETHYL ESTER; GONADOTROPIN-RELEASING HORMONE ANTAGONIZING ACTIVITY; LOW TOXICITY; ANTICARCINOGENIC AGENT; CONTRACEPTIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| US-6194419-B1 | THERAPY FOR SEXUAL DISORDERS; A 5-OXOIMIDAZOLO(1,2-A)PYRIMIDINE-6-CARBOXYLIC ESTER | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-02-27 | — | — | US | disclosed |
| EP-1042325-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033831-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134863-A1 | Preventives/remedies for alzheimer's disease | ACHE, GNRHR, PSEN1 | GAA 244/4885ALDH1A1 2627/4885TSHR 2658/4885 |
| US-20020103210-A1 | Nitrogen-containing heterocyclic compounds, their production and use | GNRHR, NR5A1, SHBG | GAA 4490/4885ALDH1A1 3645/4885TSHR 350/4885 |
| US-20050250793-A1 | Preventives/remedies for hot flash | GNRHR, SHBG, FSHR | GAA 2084/4885ALDH1A1 3063/4885TSHR 211/4885 |
| US-20090048273-A1 | PREMATURE OVULATION PREVENTIVE AGENT | GNRHR, FSHR, LHCGR | GAA 3954/4885ALDH1A1 4291/4885TSHR 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.