Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13319558 | 0.93 | KDM4E (0.43) | HKDC1KDM4EALPLGAAALDH1A1 | |
| SCHEMBL29541178 | 0.91 | ALDH1A1 (0.45) | HKDC1KDM4EALPLGAAALDH1A1 | |
| SCHEMBL20296878 | 0.91 | ALDH1A1 (0.45) | HKDC1KDM4EALPLGAAALDH1A1 | |
| SCHEMBL24860531 | 0.86 | AKR1C3 (0.42) | HKDC1KDM4EALPLGAAALDH1A1 | |
| SCHEMBL29634644 | 0.84 | ALDH1A1 (0.46) | KDM4EALPLGAAALDH1A1HSD17B10 | |
| SCHEMBL365314 | 0.84 | ALDH1A1 (0.46) | KDM4EALPLGAAALDH1A1HSD17B10 | |
| SCHEMBL24870967 | 0.84 | PTPRC (0.46) | KDM4EALPLGAAALDH1A1HSD17B10 | |
| SCHEMBL25302086 | 0.83 | ALDH1A1 (0.59) | KDM4EALPLGAAALDH1A1HSD17B10 | |
| SCHEMBL29350007 | 0.83 | ALDH1A1 (0.59) | KDM4EALPLGAAALDH1A1HSD17B10 | |
| SCHEMBL27953 | 0.83 | ALDH1A1 (0.59) | KDM4EALPLGAAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465678-B2 | Emissive polymers and devices incorporating these polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-06-18 | — | — | US | disclosed |
| US-8198096-B2 | Sensor for detection of chemical warfare agents and explosives; polyacetylenes, polyarylenevinylenes; polymers contain hexafluoroisopropanol substituent | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |
| US-20110175035-A1 | EMISSIVE POLYMERS AND DEVICES INCORPORATING THESE POLYMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-07-21 | — | — | US | disclosed |
| US-7943062-B2 | Emissive polymers and devices incorporating these polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-05-17 | — | — | US | disclosed |
| US-20100213451-A1 | EMISSIVE POLYMERS AND DEVICES INCORPORATING THESE POLYMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100137617-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2010-06-03 | — | — | US | disclosed |
| US-7662309-B2 | increased luminescent lifetimes, quantum yields and amplified emissions; polyacetylenes, polyarylenevinylenes; use in field effect transistors, detection of chemical warfare agents and explosives; solvent resistance, heat resistance | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-02-16 | — | — | US | disclosed |
| EP-1281744-B1 | Emissive polymers and devices incorporating these polymers | MASSACHUSETTS INST TECHNOLOGY (US) | 2008-09-24 | — | — | EP | disclosed |
| US-7393503-B2 | Emissive polymers and devices incorporating these polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-07-01 | — | — | US | disclosed |
| WO-2008039529-A1 | EMISSIVE POLYMERS AND DEVICES INCORPORATING THESE POLYMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-04-03 | — | — | WO | disclosed |
| US-7208122-B2 | Emissive polymers and devices incorporating these polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-04-24 | — | — | US | disclosed |
| US-20070081921-A1 | Emissive polymers and devices incorporating these polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-04-12 | — | — | US | disclosed |
| US-20060120917-A1 | Emissive polymers and devices incorporating these polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2006-06-08 | — | — | US | disclosed |
| US-20060120923-A1 | Emissive polymers and devices incorporating these polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2006-06-08 | — | — | US | disclosed |
| EP-1080162-B1 | EMISSIVE POLYMERS AND DEVICES INCORPORATING THESE POLYMERS | MASSACHUSETTS INST TECHNOLOGY (US) | 2004-03-10 | — | — | EP | disclosed |
| US-20030178607-A1 | Emissive polymers and devices incorporating these polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2003-09-25 | — | — | US | disclosed |
| EP-1281744-A2 | Emissive polymers and devices incorporating these polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2003-02-05 | — | — | EP | disclosed |
| EP-1080162-A1 | EMISSIVE POLYMERS AND DEVICES INCORPORATING THESE POLYMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999057222-A1 | EMISSIVE POLYMERS AND DEVICES INCORPORATING THESE POLYMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1999-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137617-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND | SCLY, TYR, CBS | HKDC1 2956/4885KDM4E 3311/4885ALPL 3506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.