SCHEMBL365314

SCHEMBL365314

Brc1ccccc1-c1cccc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
MAPK1 P28482 1/20 0.46
CYP2A6 P11509 3/20 0.43
TSHR P16473 2/20 0.43
HSD17B10 Q99714 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
MAOA P21397 2/20 0.42
MAOB P27338 2/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
CYP1A2 P05177 4/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
PTPN1 P18031 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALPL P05186 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29634644 1.00 ALDH1A1 (0.46) ALDH1A1MAPK1CYP2A6TSHRHSD17B10
Aniline SCHEMBL15366232 0.88 ALDH1A1 (0.42) ALDH1A1MAPK1TSHRHSD17B10TDP1
SCHEMBL13016366 0.85 ALDH1A1 (0.58) ALDH1A1MAPK1CA12CA1CA2
SCHEMBL23187820 0.85 ALDH1A1 (0.50) ALDH1A1MAPK1CYP2A6TSHRHSD17B10
SCHEMBL29350007 0.84 ALDH1A1 (0.59) ALDH1A1MAPK1CYP2A6TSHRHSD17B10
SCHEMBL27953 0.84 ALDH1A1 (0.59) ALDH1A1MAPK1CYP2A6TSHRHSD17B10
SCHEMBL25302086 0.84 ALDH1A1 (0.59) ALDH1A1MAPK1CYP2A6TSHRHSD17B10
SCHEMBL29490404 0.84 CYP1A2 (0.52) ALDH1A1CYP2A6TSHRHSD17B10TDP1
SCHEMBL1776407 0.84 HKDC1 (0.46) ALDH1A1MAPK1CYP2A6TSHRHSD17B10
SCHEMBL947346 0.84 CYP1A2 (0.52) ALDH1A1CYP2A6TSHRHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103848967-B A kind of containing thienothiophene, diazosulfide and cyclopentano two thiophen polymer and preparation and application thereof Haiyangwang Lighting Technology Co., Ltd. (CN) 2016-01-27 CN claimed
CN-103848967-A Polymer containing thienothiophene, benzothiadiazole and cyclopentadithiophene, preparation method and application thereof OCEANS KING LIGHTING SCIENCE 2014-06-11 CN claimed
CN-101475433-A Anthryl derivative and preparation thereof HEBEI DELONGTAI CHEMICALS CO L (CN) 2009-07-08 CN claimed
US-20260035339-A1 TETRAHYDRONAPHTHALENE DERIVATIVE ATRANSEN PHARMA LTD (JP) 2026-02-05 US disclosed
EP-4095124-B1 ARYLAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2025-12-24 EP disclosed
US-12486230-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2025-12-02 US disclosed
US-12274163-B2 Compound for organic electrical element, organic electrical element using same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2025-04-08 US disclosed
EP-4501906-A1 TETRAHYDRONAPHTHALENE DERIVATIVE Atransen Pharma Ltd. (JP) 2025-02-05 EP disclosed
EP-4269406-B1 COMPOUND FOR ORGANIC ELECTRICAL ELEMENT, ORGANIC ELECTRICAL ELEMENT USING SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO LTD (KR) 2024-07-10 EP disclosed
EP-4269406-B1 COMPOUND FOR ORGANIC ELECTRICAL ELEMENT, ORGANIC ELECTRICAL ELEMENT USING SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO LTD (KR) 2024-07-10 EP disclosed
CN-118271283-A Synthesis method of 9, 10-dithio (hetero) phenanthrene 中南大学 2024-07-02 CN disclosed
EP-1494667-A1 IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS Pfizer Japan Inc. (JP) 2005-01-12 EP disclosed
US-20040214035-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. 2004-10-28 US disclosed
US-20030220372-A1 Imidazole compounds as anti-inflammatory and analgesic agents HIRANO MISATO (JP) 2003-11-27 US disclosed
WO-2003086390-A1 IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS PFIZER JAPAN INC. (JP) 2003-10-23 WO disclosed
EP-1354887-A1 Ligands for metals and improved metal-catalyzed processes based thereon Massachusetts Insitute of Technology (US) 2003-10-22 EP disclosed
EP-1333018-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2003-08-06 EP disclosed
CN-1394195-A Organic electroluminescent element IDEMITSU KOSAN CO (JP) 2003-01-29 CN disclosed
EP-1097158-A2 LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2001-05-09 EP disclosed
WO-2000002887-A2 LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2000-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12486230-B2 Materials for organic electroluminescent devices L1CAM, EFNA1, EPCAM ALDH1A1 33/4885MAPK1 427/4885CYP2A6 1726/4885
US-12274163-B2 Compound for organic electrical element, organic electrical element using same and electronic device thereof PIEZO1, ASIC1, TMEM109 ALDH1A1 664/4885MAPK1 357/4885CYP2A6 1830/4885
US-20260035339-A1 TETRAHYDRONAPHTHALENE DERIVATIVE LATS1, LATS2, BCAT1 ALDH1A1 1267/4885MAPK1 152/4885CYP2A6 1376/4885
US-20030220372-A1 Imidazole compounds as anti-inflammatory and analgesic agents PTGS1, PTGS2, PTGES ALDH1A1 248/4885MAPK1 570/4885CYP2A6 134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.