Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | WRN | Q14191 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL211511 | 0.87 | MGLL (0.48) | MGLLTHRBTSHRALDH1A1CYP1A2 | |
| SCHEMBL17767388 | 0.85 | OPRM1 (0.42) | MGLLTHRBAKT1TSHRALDH1A1 | |
| SCHEMBL17286211 | 0.84 | HTT (0.42) | THRBL3MBTL1TSHRALDH1A1HPGD | |
| SCHEMBL12705829 | 0.83 | SMN1; SMN2 (0.49) | L3MBTL1TSHRALDH1A1HPGDLMNA | |
| SCHEMBL13309619 | 0.82 | THRB (0.38) | THRBL3MBTL1TSHRALDH1A1LMNA | |
| SCHEMBL2403793 | 0.80 | THRB (0.53) | THRBL3MBTL1TSHRALDH1A1ACHE | |
| SCHEMBL13872030 | 0.80 | THRB (0.53) | THRBL3MBTL1TSHRALDH1A1ACHE | |
| SCHEMBL14764411 | 0.79 | TSHR (0.49) | MGLLTHRBTSHRALDH1A1CYP1A2 | |
| SCHEMBL13799114 | 0.78 | ACHE (0.60) | MGLLACHE | |
| SCHEMBL4141287 | 0.77 | MGLL (0.47) | MGLLAKT1ALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221698-B1 | POROUS MEMBRANES WITH A POLYMER GRAFTING, METHODS AND USES THEREOF | Global Life Sciences Solutions Operations UK Ltd (GB) | 2021-02-17 | — | — | EP | claimed |
| CN-107003306-B | Porous membranes with polymer grafts, methods and uses thereof | 通用电气公司 | 2020-07-03 | — | — | CN | disclosed |
| WO-2016079171-A1 | DEVICE COMPRISING POROUS MEMBRANES WITH A POLYMER GRAFTING, METHODS AND USES THEREOF | GENERAL ELECTRIC COMPANY (US) | 2016-05-26 | — | — | WO | disclosed |
| US-20160146795-A1 | POROUS MEMBRANES WITH A POLYMER GRAFTING, METHODS AND USES THEREOF | GENERAL ELECTRIC COMPANY | 2016-05-26 | — | — | US | disclosed |
| WO-2016079171-A1 | DEVICE COMPRISING POROUS MEMBRANES WITH A POLYMER GRAFTING, METHODS AND USES THEREOF | GENERAL ELECTRIC COMPANY (US) | 2016-05-26 | — | — | WO | disclosed |
| US-20160146802-A1 | POROUS MEMBRANES WITH A POLYMER GRAFTING, METHODS AND USES THEREOF | Global Life Sciences Solutions Operations UK Ltd (GB) | 2016-05-26 | — | — | US | disclosed |