Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPC | P11150 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19689650 | 0.90 | GPR52 (0.35) | RPS6KB1KDM1AMAOAMAOBSTAT3 | |
| SCHEMBL17778738 | 0.90 | LIPG (0.36) | RPS6KB1KDM1AMAOAMAOBCA2 | |
| SCHEMBL17778631 | 0.89 | CA2 (0.34) | RPS6KB1KDM1AMAOAMAOBHPGDS | |
| SCHEMBL19706655 | 0.88 | KDM1A (0.34) | RPS6KB1KDM1AMAOAMAOBHPGDS | |
| SCHEMBL17768097 | 0.88 | KDM1A (0.34) | RPS6KB1KDM1AMAOAMAOBHPGDS | |
| SCHEMBL19670287 | 0.86 | PHGDH (0.38) | RPS6KB1KDM1AMAOAMAOBHPGDS | |
| SCHEMBL16754360 | 0.85 | RAF1 (0.36) | RPS6KB1KDM1AMAOAMAOBCA2 | |
| SCHEMBL16754334 | 0.85 | RAF1 (0.36) | RPS6KB1KDM1AMAOAMAOBCA2 | |
| SCHEMBL16754361 | 0.85 | RAF1 (0.36) | RPS6KB1KDM1AMAOAMAOBCA2 | |
| SCHEMBL17778753 | 0.84 | GRIN1 (0.33) | RPS6KB1KDM1AMAOAMAOBCHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079709-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |