SCHEMBL17784174

SCHEMBL17784174

Cc1cc(C)c(-c2[c]c3[nH]c4ccccc4c3cc2)c(C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 5/20 0.46
ABCB1 P08183 1/20 0.42
CYP1A2 P05177 2/20 0.39
CYP2C19 P33261 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
ALDH1A1 P00352 4/20 0.38
HSD17B10 Q99714 3/20 0.38
HPGD P15428 2/20 0.38
GAA P10253 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
ALOX15 P16050 1/20 0.38
PARP1 P09874 1/20 0.38
GPR3 P46089 1/20 0.37
KDM4E B2RXH2 2/20 0.37
MAPT P10636 2/20 0.37
ATM Q13315 1/20 0.37
AHR P35869 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15848111 0.84 GRIA1 (0.34) KIF11TNKS2RXFP1
SCHEMBL1426545 0.77 KIF11 (0.48) KIF11CYP1A2CYP2C19TNKS2ALDH1A1
SCHEMBL1323291 0.74 ESR1 (0.47) KIF11CYP1A2TNKS2ALDH1A1HSD17B10
SCHEMBL11192699 0.72 RAB9A (0.45) KIF11CYP1A2CYP2C19ALDH1A1HSD17B10
SCHEMBL1427044 0.71 MAPT (0.46) KIF11CYP1A2CYP2C19TNKS2ALDH1A1
SCHEMBL16516043 0.70 ALDH1A1 (0.38) KIF11CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL20841423 0.70 BCHE (0.48) KIF11CYP1A2TNKS2ALDH1A1HSD17B10
SCHEMBL11143149 0.69 LRRK2 (0.43) CYP1A2ALDH1A1HSD17B10HPGDGAA
SCHEMBL768750 0.69 GABRP (0.46) KIF11ALDH1A1HSD17B10HPGDGAA
SCHEMBL1726238 0.69 IDO1 (0.49) CYP1A2ALDH1A1HSD17B10HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108377649-B Polymerization process for producing ethylene-based polymers 陶氏环球技术有限责任公司 2021-04-23 CN claimed
CN-110546171-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2023-02-28 CN disclosed
CN-109963886-B Phosphoguanidine group IV metal olefin polymerization catalyst 陶氏环球技术有限责任公司 2023-01-06 CN disclosed
CN-115260366-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-11-01 CN disclosed
CN-108779582-B Artificial turf and method for producing same 陶氏环球技术有限责任公司 2022-10-11 CN disclosed
CN-110582518-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-08-09 CN disclosed
CN-108779205-B Olefin polymerization catalyst 陶氏环球技术有限责任公司 2022-01-07 CN disclosed
CN-109963884-B Doubly-linked phosphaguanidine group IV metal complexes and olefin polymerization catalysts therefrom 陶氏环球技术有限责任公司 2021-11-09 CN disclosed
CN-108350121-B Procatalyst and polymerization process using the same 陶氏环球技术有限责任公司 2021-10-01 CN disclosed
CN-109952326-B Thiourea group IV transition metal catalysts and polymerization systems 陶氏环球技术有限责任公司 2021-08-10 CN disclosed
CN-113201084-A Molecular weight control of polyolefins using halogenated bisphenylphenoxy catalysts 陶氏环球技术有限责任公司 2021-08-03 CN disclosed
CN-108884196-B Olefin polymerization catalyst system and method of using same 陶氏环球技术有限责任公司 2021-06-18 CN disclosed
CN-108779204-B Olefin polymerization catalyst system and method of using same 陶氏环球技术有限责任公司 2021-06-18 CN disclosed
CN-108377649-B Polymerization process for producing ethylene-based polymers 陶氏环球技术有限责任公司 2021-04-23 CN disclosed
CN-112004818-A Silicon-terminated organometallic compounds and methods of making the same 陶氏环球技术有限责任公司 2020-11-27 CN disclosed
CN-107108804-B Polyolefin composition and process for producing the same 陶氏环球技术有限责任公司 2020-07-24 CN disclosed
CN-107208339-B Cushioning net structure and method for manufacturing same 陶氏环球技术有限责任公司 2020-06-23 CN disclosed
CN-110582518-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2019-12-17 CN disclosed
CN-110546171-A catalyst system for forming multi-block copolymers DOW GLOBAL TECHNOLOGIES LLC 2019-12-06 CN disclosed
US-20160152903-A1 PROCESS FOR THE PREPARATION OF BRANCHED POLYOLEFINS FOR LUBRICANT APPLICATIONS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC 2016-06-02 US disclosed