SCHEMBL17790367

SCHEMBL17790367

COc1ccc(N2C(=O)C(C#N)=C(C)/C(=C\c3ccc(N(c4ccccc4)c4cccc5ccccc45)s3)C2=O)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
TDP1 Q9NUW8 1/20 0.34
KMT2A Q03164 8/20 0.34
MEN1 O00255 7/20 0.34
ALDH1A1 P00352 6/20 0.34
KDM4E B2RXH2 5/20 0.34
RECQL P46063 2/20 0.34
LMNA P02545 2/20 0.34
POLB P06746 1/20 0.34
THRB P10828 1/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
HSD11B1 P28845 1/20 0.33
USP2 O75604 1/20 0.32
TUBB4A P04350 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17790366 0.93 MAPT (0.31) MAPTL3MBTL1TDP1KMT2AMEN1
SCHEMBL17784182 0.84 ALDH1A1 (0.33) MAPTL3MBTL1TDP1KMT2AMEN1
SCHEMBL17784181 0.84 ALDH1A1 (0.33) MAPTL3MBTL1TDP1KMT2AMEN1
SCHEMBL25870837 0.84 ALDH1A1 (0.33) MAPTL3MBTL1TDP1KMT2AMEN1
SCHEMBL18913206 0.78 ESR2 (0.33) MAPTL3MBTL1TDP1KMT2AMEN1
SCHEMBL25870834 0.76 KDM4E (0.31) MAPTL3MBTL1TDP1KMT2AMEN1
SCHEMBL18882681 0.74 MEN1 (0.39) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL18913208 0.73 KDM4E (0.32) MAPTL3MBTL1TDP1KMT2AMEN1
SCHEMBL17790364 0.73 MAPT (0.38) MAPTL3MBTL1TDP1KMT2AMEN1
SCHEMBL28704979 0.71 SIGMAR1 (0.31) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11711930-B2 2023-07-25 US disclosed
US-11532671-B2 Organic photoelectronic device and image sensor SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-12-20 US disclosed
US-11005070-B2 Organic photoelectronic device and image sensor and electronic device SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-05-11 US disclosed
US-10998514-B2 Photoelectric devices and image sensors and electronic devices SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-05-04 US disclosed
US-20200127232-A1 ORGANIC PHOTOELECTRONIC DEVICE AND IMAGE SENSOR AND ELECTRONIC DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-04-23 US disclosed
US-10381412-B2 Organic photoelectronic device SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-08-13 US disclosed
US-20190173032-A1 PHOTOELECTRIC DEVICES AND IMAGE SENSORS AND ELECTRONIC DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-06-06 US disclosed
US-20190157594-A1 ORGANIC PHOTOELECTRONIC DEVICE AND IMAGE SENSOR SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-05-23 US disclosed
US-10290812-B2 Compound for organic photoelectric device and organic photoelectric device image sensor, and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-05-14 US disclosed
US-10236461-B2 Organic photoelectronic device and image sensor SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-03-19 US disclosed
US-20180062112-A1 ORGANIC PHOTOELECTRONIC DEVICE AND IMAGE SENSOR AND ELECTRONIC DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-03-01 US disclosed
US-20170338431-A1 ORGANIC PHOTOELECTRONIC DEVICE AND IMAGE SENSOR SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-11-23 US disclosed
US-9786847-B2 Compound for organic photoelectric device, and organic photoelectric device and image sensor including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-10-10 US disclosed
US-9786847-B2 Compound for organic photoelectric device, and organic photoelectric device and image sensor including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-10-10 US disclosed
US-20170154929-A1 ORGANIC PHOTOELECTRONIC DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-06-01 US disclosed
US-20160155954-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, AND ORGANIC PHOTOELECTRIC DEVICE AND IMAGE SENSOR INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-02 US disclosed
US-20160155954-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, AND ORGANIC PHOTOELECTRIC DEVICE AND IMAGE SENSOR INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290812-B2 Compound for organic photoelectric device and organic photoelectric device image sensor, and electronic device including the same PPOX, OCIAD1, CRY1 MAPT 1146/4885L3MBTL1 3479/4885TDP1 1282/4885
US-20160155954-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, AND ORGANIC PHOTOELECTRIC DEVICE AND IMAGE SENSOR INCLUDING THE SAME PPOX, PIEZO1, CRY1 MAPT 1741/4885L3MBTL1 3572/4885TDP1 1242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.