Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1636013 | 0.82 | TAS2R14 (0.40) | TAS2R14PTGER4ALDH1A1HSD17B10HPGD | |
| SCHEMBL19075046 | 0.77 | PKM (0.31) | PKM | |
| SCHEMBL412257 | 0.77 | TAS2R14 (0.42) | TAS2R14ALDH1A1PKMHSD17B10HPGD | |
| SCHEMBL19075043 | 0.73 | TSHR (0.30) | TDP1 | |
| SCHEMBL1781054 | 0.73 | HCRTR1 (0.34) | TDP1 | |
| SCHEMBL10053348 | 0.71 | TAS2R14 (0.51) | TAS2R14ALDH1A1HSD17B10HPGDNOTUM | |
| SCHEMBL23284008 | 0.71 | AR (0.36) | TAS2R14ALDH1A1HSD17B10HPGDNOTUM | |
| SCHEMBL30634615 | 0.69 | TAS2R14 (0.45) | TAS2R14ALDH1A1HSD17B10HPGDNOTUM | |
| SCHEMBL27466963 | 0.69 | TAS2R14 (0.45) | TAS2R14ALDH1A1HSD17B10HPGDNOTUM | |
| SCHEMBL1634606 | 0.69 | TAS2R14 (0.45) | TAS2R14ALDH1A1HSD17B10HPGDNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167473-B1 | 3-CYCLOPROPYL-4-(3-THIOBENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES | BAYER IP GMBH (DE) | 2017-07-05 | — | — | EP | disclosed |
| CN-101679285-B | 3-cyclopropyl-4-(3-thiobenzoyl)pyrazoles and their use as herbicides | BAYER CROPSCIENCE AG | 2013-07-24 | — | — | CN | disclosed |
| US-7943551-B2 | 3-cyclopropyl-4-(3-thiobenzoyl) pyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2011-05-17 | — | — | US | disclosed |
| EP-2167473-A2 | 3-CYCLOPROPYL-4-(3-THIOBENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES | Bayer CropScience AG (DE) | 2010-03-31 | — | — | EP | disclosed |
| CN-101679285-A | 3-cyclopropyl-4-(3-thiobenzoyl) pyrazoles and as the purposes of weedicide | BAYER CROPSCIENCE AG | 2010-03-24 | — | — | CN | disclosed |
| WO-2008151719-A2 | 3-CYCLOPROPYL-4-(3-THIOBENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-12-18 | — | — | WO | disclosed |
| US-20080305956-A1 | 3-Cyclopropyl-4-(3-Thiobenzoyl) Pyrazoles And Their Use as Herbicides | BAYER CROPSCIENCE AG (US) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080305956-A1 | 3-Cyclopropyl-4-(3-Thiobenzoyl) Pyrazoles And Their Use as Herbicides | TH, GLRX3, DDT | TAS2R14 637/4885PTGER4 1138/4885ALDH1A1 856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.