Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LIG1 | P18858 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | HAAO | P46952 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419198 | 0.89 | TAS2R14 (0.35) | TAS2R14NOTUMRXRARXRBSORT1 | |
| SCHEMBL1230305 | 0.83 | NOTUM (0.39) | TAS2R14NOTUMRXRARXRBSORT1 | |
| SCHEMBL1636013 | 0.83 | TAS2R14 (0.40) | TAS2R14NOTUMRXRARXRBSORT1 | |
| SCHEMBL29276544 | 0.82 | KDM4E (0.42) | TAS2R14NOTUMRXRARXRBSORT1 | |
| SCHEMBL21192829 | 0.82 | CLCN2 (0.42) | TAS2R14NOTUMRXRARXRBSORT1 | |
| SCHEMBL10053348 | 0.80 | TAS2R14 (0.51) | TAS2R14NOTUMRXRARXRBSORT1 | |
| SCHEMBL976616 | 0.80 | NOTUM (0.39) | TAS2R14NOTUMRXRARXRBSORT1 | |
| SCHEMBL31440663 | 0.80 | NOTUM (0.39) | TAS2R14NOTUMRXRARXRBSORT1 | |
| SCHEMBL1231027 | 0.80 | TDP1 (0.41) | TAS2R14NOTUMRXRARXRBKDM4E | |
| SCHEMBL9440024 | 0.79 | CLCN2 (0.45) | TAS2R14NOTUMRXRARXRBSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349883-B | Method for synthesizing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acid | 拜耳作物科学股份公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-108349885-B | Method for producing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acids by chemoselective thioether oxidation | 拜耳作物科学股份公司 | 2020-05-15 | — | — | CN | disclosed |
| EP-3368510-B1 | METHOD FOR THE PREPARATION OF 2-ALKYL-4-TRIFLUORMETHYL-3-ALKYLSULFONYL BENZOIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2020-02-19 | — | — | EP | disclosed |
| US-10435352-B2 | Method for synthesizing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acids | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-10-08 | — | — | US | disclosed |
| EP-3383843-B1 | METHOD FOR PRODUCING 2-ALKYL-4-TRIFLUOROMETHYL-3-ALKYL SULFONYL BENZOIC ACIDS BY CHEMOSELECTIVE THIOETHER OXIDATION | BAYER CROPSCIENCE AG (DE) | 2019-09-25 | — | — | EP | disclosed |
| US-10252990-B2 | Process for the preparation of 2-alkyl-4-trifluoromethyl-3-alkylsulphonylbenzoic acids by chemoselective thioether oxidation | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-04-09 | — | — | US | disclosed |
| US-20180354898-A1 | Process for the preparation of 2-alkyl-4-trifluoromethyl-3-alkylsulphonylbenzoic acids by chemoselective thioether oxidation | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-12-13 | — | — | US | disclosed |
| US-20180305302-A1 | METHOD FOR SYNTHESIZING 2-ALKYL-4-TRIFLUOROMETHYL-3-ALKYLSULFONYLBENZOIC ACIDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-10-25 | — | — | US | disclosed |
| EP-3383843-A1 | METHOD FOR PRODUCING 2-ALKYL-4-TRIFLUOROMETHYL-3-ALKYL SULFONYL BENZOIC ACIDS BY CHEMOSELECTIVE THIOETHER OXIDATION | Bayer CropScience Aktiengesellschaft (DE) | 2018-10-10 | — | — | EP | disclosed |
| EP-3368510-A1 | METHOD FOR SYNTHESIZING 2-ALKYL-4-TRIFLUOROMETHYL-3-ALKYLSULFONYLBENZOIC ACIDS | Bayer CropScience Aktiengesellschaft (DE) | 2018-09-05 | — | — | EP | disclosed |
| US-8563779-B2 | (4-trifluoromethyl-3-thiobenzoyl)cyclohexanediones and use thereof as herbicides | BAYER CROPSCIENCE AG (DE) | 2013-10-22 | — | — | US | disclosed |
| EP-2595954-A1 | (4-TRIFLUORMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | Bayer Intellectual Property GmbH (DE) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010574-A1 | (4-TRIFLUORMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | WO | disclosed |
| US-20120021902-A1 | (4-TRIFLUOROMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | US | disclosed |
| US-7932211-B2 | 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2011-04-26 | — | — | US | disclosed |
| EP-2137160-B1 | 4-(4-TRIFLUOROMETHYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-10-27 | — | — | EP | disclosed |
| EP-2137160-A1 | 4-(4-TRIFLUOROMETHYL-3-THIOBENZOYL)PYRAZOLES, AND USE THEREOF AS HERBICIDES | Bayer CropScience AG (DE) | 2009-12-30 | — | — | EP | disclosed |
| US-20090069184-A1 | 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2009-03-12 | — | — | US | disclosed |
| WO-2008125214-A1 | 4-(4-TRIFLUOROMETHYL-3-THIOBENZOYL)PYRAZOLES, AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | WO | disclosed |
| EP-1980556-A1 | 4-(4-trifluor methyl-3-thiobenzoyl) pyrazoles and their application as herbicides | Bayer CropScience AG (DE) | 2008-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305302-A1 | METHOD FOR SYNTHESIZING 2-ALKYL-4-TRIFLUOROMETHYL-3-ALKYLSULFONYLBENZOIC ACIDS | ARSA, ABL1, CYP2B6 | TAS2R14 4297/4885NOTUM 3066/4885RXRA 1268/4885 |
| US-20180354898-A1 | Process for the preparation of 2-alkyl-4-trifluoromethyl-3-alkylsulphonylbenzoic acids by chemoselective thioether oxidation | TST, CYP2F1, SULT1A1 | TAS2R14 2285/4885NOTUM 2517/4885RXRA 1572/4885 |
| US-20120021902-A1 | (4-TRIFLUOROMETHYL-3-THIOBENZOYL)CYCLOHEXANEDIONES AND USE THEREOF AS HERBICIDES | CBR3, DDT, CYP4X1 | TAS2R14 1358/4885NOTUM 1045/4885RXRA 427/4885 |
| US-20090069184-A1 | 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles and their use as herbicides | TH, DDT, CYP4X1 | TAS2R14 442/4885NOTUM 1266/4885RXRA 733/4885 |
| US-10435352-B2 | Method for synthesizing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acids | ARSA, ABL1, CYP2B6 | TAS2R14 4297/4885NOTUM 3066/4885RXRA 1268/4885 |
| US-10252990-B2 | Process for the preparation of 2-alkyl-4-trifluoromethyl-3-alkylsulphonylbenzoic acids by chemoselective thioether oxidation | TST, CYP2F1, SULT1A1 | TAS2R14 2285/4885NOTUM 2517/4885RXRA 1572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.