Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23283981 | 0.85 | DAO (0.37) | TAS2R14DAONOTUMRXRARXRB | |
| SCHEMBL412257 | 0.83 | TAS2R14 (0.42) | TAS2R14DAONOTUMRXRARXRB | |
| SCHEMBL1779061 | 0.82 | TAS2R14 (0.36) | TAS2R14NOTUMRXRARXRBPTGER4 | |
| SCHEMBL10053348 | 0.77 | TAS2R14 (0.51) | TAS2R14DAONOTUMRXRARXRB | |
| SCHEMBL598479 | 0.76 | ALDH1A1 (0.42) | NOTUMKDM4EALDH1A1HPGDUSP2 | |
| SCHEMBL23284003 | 0.76 | KIF11 (0.37) | DAOALDH1A1CTSSCYP2C19 | |
| SCHEMBL8494765 | 0.75 | PTGDR2 (0.45) | TAS2R14RXRARXRBKDM4EALDH1A1 | |
| SCHEMBL1634766 | 0.74 | RAB9A (0.36) | ALDH1A1CYP2C19 | |
| SCHEMBL30634615 | 0.74 | TAS2R14 (0.45) | TAS2R14DAONOTUMRXRARXRB | |
| SCHEMBL27466963 | 0.74 | TAS2R14 (0.45) | TAS2R14DAONOTUMRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932211-B2 | 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2011-04-26 | — | — | US | disclosed |
| EP-2137160-B1 | 4-(4-TRIFLUOROMETHYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-10-27 | — | — | EP | disclosed |
| EP-2137160-A1 | 4-(4-TRIFLUOROMETHYL-3-THIOBENZOYL)PYRAZOLES, AND USE THEREOF AS HERBICIDES | Bayer CropScience AG (DE) | 2009-12-30 | — | — | EP | disclosed |
| US-20090069184-A1 | 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2009-03-12 | — | — | US | disclosed |
| WO-2008125214-A1 | 4-(4-TRIFLUOROMETHYL-3-THIOBENZOYL)PYRAZOLES, AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | WO | disclosed |
| EP-1980556-A1 | 4-(4-trifluor methyl-3-thiobenzoyl) pyrazoles and their application as herbicides | Bayer CropScience AG (DE) | 2008-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069184-A1 | 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles and their use as herbicides | TH, DDT, CYP4X1 | TAS2R14 442/4885DAO 169/4885NOTUM 1266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.