SCHEMBL177916

SCHEMBL177916

COc1ccc(Oc2ccc(N)cc2)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.84
MAPK1 P28482 2/20 0.84
ALDH1A1 P00352 7/20 0.80
CYP3A4 P08684 2/20 0.80
TSHR P16473 1/20 0.74
SMN1; SMN2 Q16637 4/20 0.69
TEAD4 Q15561 1/20 0.65
APP P05067 2/20 0.64
NR4A1 P22736 1/20 0.64
MAPT P10636 5/20 0.62
POLB P06746 1/20 0.62
LTA4H P09960 2/20 0.61
MAOA P21397 2/20 0.61
MAOB P27338 1/20 0.58
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
CA14 Q9ULX7 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL23748586 0.97 ALDH1A1 (0.85) TDP1MAPK1ALDH1A1CYP3A4TSHR
SCHEMBL4985207 0.93 TDP1 (0.73) TDP1MAPK1ALDH1A1CYP3A4TSHR
SCHEMBL8526630 0.92 TDP1 (1.00) TDP1MAPK1ALDH1A1CYP3A4TSHR
SCHEMBL5097 0.92
Anisole SCHEMBL28723995 0.91 LTA4H (0.78) TDP1MAPK1ALDH1A1CYP3A4TSHR
4-Phenoxyaniline SCHEMBL8216658 0.91 LTA4H (0.78) TDP1MAPK1ALDH1A1CYP3A4TSHR
Hydrochloric Acid SCHEMBL208637 0.89 ALDH1A1 (1.00) TDP1MAPK1ALDH1A1CYP3A4TSHR
Methane SCHEMBL22289589 0.89 TDP1 (0.94) TDP1MAPK1ALDH1A1CYP3A4TSHR
SCHEMBL21840887 0.89 TDP1 (0.94) TDP1MAPK1ALDH1A1CYP3A4TSHR
Hydrochloric Acid SCHEMBL3947579 0.89 ALDH1A1 (1.00) TDP1MAPK1ALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116789574-B Preparation method and application of camphorsulfonamide compound containing diphenyl ether group 南京林业大学 2024-07-30 CN claimed
CN-113880765-B 4- (1H-pyrazol-1-yl) biphenyl formamide compound containing diphenyl ether group and application thereof 南京林业大学 2023-04-28 CN claimed
EP-3797991-B1 PREPREG AND PRODUCTION METHOD THEREFOR, SLIT TAPE PREPREG, CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2025-10-29 EP disclosed
US-12448510-B2 Prepreg, method for producing same, and slit tape prepreg TORAY INDUSTRIES, INC. (JP) 2025-10-21 US disclosed
EP-3995536-B1 PREPREG AND FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2025-06-18 EP disclosed
CN-119912506-A 1, 2-Diaza-5-carboxamide compound, preparation method and application thereof 沈阳药科大学 2025-05-02 CN disclosed
CN-119913525-A Electrochemical synthesis method of 3-aryl quinoxalinone compound 新疆大学 2025-05-02 CN disclosed
CN-113164495-B Covalent targeting of E3 ligases 加利福尼亚大学董事会 2025-04-22 CN disclosed
US-20250120982-A1 COVALENT TARGETING OF E3 LIGASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-04-17 US disclosed
US-20250051335-A1 TAU-TUBULIN KINASE (TTBK) INHIBITOR COMPOUNDS CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2025-02-13 US disclosed
US-12161648-B2 Covalent targeting of E3 ligases THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-12-10 US disclosed
EP-0198369-A2 Process for the preparation of perylene-3,4,9,10-tetracarboxylic-acid aryl imides HOECHST AKTIENGESELLSCHAFT (DE) 1986-10-22 EP disclosed
EP-0113922-A2 Process for the manufacture of cationic methine dyes BAYER AG (DE) 1984-07-25 EP disclosed
EP-0113921-A2 Process for the manufacture of stable solutions of cationic methine dyes BAYER AG (DE) 1984-07-25 EP disclosed
EP-0113920-A2 Process for the manufacture of stable solutions of cationic methine dyes, and their use in spin dyeing BAYER AG (DE) 1984-07-25 EP disclosed
US-4386002-A HIGH PRESSURE APPLICATIONS UOP INC. (US) 1983-05-31 US disclosed
US-4380497-A Amines of alkoxydiphenyl esthers as antioxidants and lubricating oils and greases containing same UOP INC. (US) 1983-04-19 US disclosed
US-4279637-A Herbicidal N-substituted 4-imidazolin-2-ones VELSICOL CHEMICAL CORPORATION (US) 1981-07-21 US disclosed
US-3975379-A METHINE BAYER AKTIENGESELLSCHAFT (DT) 1976-08-17 US disclosed
US-3956264-A Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12161648-B2 Covalent targeting of E3 ligases RNF114, RNF4, RNF168 TDP1 1403/4885MAPK1 4047/4885ALDH1A1 2969/4885
US-20250051335-A1 TAU-TUBULIN KINASE (TTBK) INHIBITOR COMPOUNDS TTBK1, TTBK2, MAPT TDP1 78/4885MAPK1 427/4885ALDH1A1 3733/4885
US-20250120982-A1 COVALENT TARGETING OF E3 LIGASES STUB1, XIAP, RBX1 TDP1 1234/4885MAPK1 4314/4885ALDH1A1 2485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.