SCHEMBL17794012

SCHEMBL17794012

CCCCCCCCCCCCc1c2cc(Br)sc2c(C)c2cc(Br)sc12

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 6/20 0.40
SRC P12931 1/20 0.33
ALOX5 P09917 5/20 0.32
PTGS2 P35354 2/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TYR P14679 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL337083 0.94 GPR35 (0.43) GPR35SRCALOX5PTGS2KDM4E
SCHEMBL14706992 0.94 GPR35 (0.43) GPR35SRCALOX5PTGS2KDM4E
SCHEMBL3842117 0.94 GPR35 (0.43) GPR35SRCALOX5PTGS2KDM4E
SCHEMBL995558 0.94 GPR35 (0.43) GPR35SRCALOX5PTGS2KDM4E
SCHEMBL991738 0.87 GPR35 (0.43) GPR35SRCALOX5PTGS2KDM4E
SCHEMBL2679142 0.87 GPR35 (0.43) GPR35SRCALOX5PTGS2KDM4E
SCHEMBL3371736 0.85 GPR35 (0.41) GPR35SRCALOX5PTGS2KDM4E
SCHEMBL14882940 0.81 GPR35 (0.40) GPR35SRCALOX5PTGS2KDM4E
SCHEMBL23812254 0.79 ACE2 (0.35) GPR35
SCHEMBL16323051 0.79 LMNA (0.33) GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160152639-A1 POLYMERIC COMPOUND AND ELECTRONIC ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160152639-A1 POLYMERIC COMPOUND AND ELECTRONIC ELEMENT ARPC2, AXIN2, EMC2 GPR35 2791/4885SRC 1080/4885ALOX5 2415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.