SCHEMBL337083

SCHEMBL337083

CCCCCCCCCCCCc1c2cc(Br)sc2c(CCCCCCCCCCCC)c2cc(Br)sc12

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 6/20 0.43
PTGS2 P35354 2/20 0.35
ALOX5 P09917 5/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
SRC P12931 1/20 0.33
CYP19A1 P11511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14706992 1.00 GPR35 (0.43) GPR35PTGS2ALOX5KDM4EALDH1A1
SCHEMBL3842117 1.00 GPR35 (0.43) GPR35PTGS2ALOX5KDM4EALDH1A1
SCHEMBL995558 1.00 GPR35 (0.43) GPR35PTGS2ALOX5KDM4EALDH1A1
SCHEMBL17794012 0.94 GPR35 (0.40) GPR35PTGS2ALOX5KDM4EALDH1A1
SCHEMBL991738 0.93 GPR35 (0.43) GPR35PTGS2ALOX5KDM4EALDH1A1
SCHEMBL2679142 0.93 GPR35 (0.43) GPR35PTGS2ALOX5KDM4EALDH1A1
SCHEMBL3371736 0.91 GPR35 (0.41) GPR35PTGS2ALOX5KDM4EALDH1A1
SCHEMBL14882940 0.87 GPR35 (0.40) GPR35PTGS2ALOX5KDM4EALDH1A1
SCHEMBL23812254 0.84 ACE2 (0.35) GPR35
SCHEMBL16323051 0.84 LMNA (0.33) GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3010992-B1 CONJUGATED POLYMERS RAYNERGY TEK INC (TW) 2021-09-15 EP disclosed
EP-3243818-B1 POLYMERS OF BENZODITHIOPHENE AND THEIR USE AS ORGANIC SEMICONDUCTORS RAYNERGY TEK INC (TW) 2021-02-17 EP disclosed
US-10158079-B2 Polymers of benzodithiophene and their use as organic semiconductors MERCK PATENT GMBH (DE) 2018-12-18 US disclosed
US-9985211-B2 Conjugated polymers MERCK PATENT GMBH (DE) 2018-05-29 US disclosed
US-9985211-B2 Conjugated polymers MERCK PATENT GMBH (DE) 2018-05-29 US disclosed
EP-2626375-B1 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2017-11-22 EP disclosed
EP-2626375-B1 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2017-11-22 EP disclosed
EP-3243818-A1 POLYMERS OF BENZODITHIOPHENE AND THEIR USE AS ORGANIC SEMICONDUCTORS Merck Patent GmbH (DE) 2017-11-15 EP disclosed
EP-2560965-B1 POLYMERS OF BENZODITHIOPHENE AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2017-06-14 EP disclosed
US-9650461-B2 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2017-05-16 US disclosed
EP-1916250-B1 Electronic devices comprising poly(dithienyl-benzodithiophenes) as semiconductors XEROX CORP (US) 2011-01-05 EP disclosed
US-7834132-B2 Electronic devices XEROX CORPORATION (US) 2010-11-16 US disclosed
US-7820782-B2 Poly(dithienylbenzo[1,2-b:4,5-b′]dithiophene) polymers XEROX CORPORATION (US) 2010-10-26 US disclosed
EP-2213692-A1 Polymer Semiconductors with High Mobility Xerox Corporation (US) 2010-08-04 EP disclosed
US-20100121004-A1 PURIFICATION PROCESS FOR SEMICONDUCTING MONOMERS XEROX CORPORATION (US) 2010-05-13 US disclosed
US-20090181509-A1 POLYMER SEMICONDUCTORS WITH HIGH MOBILITY XEROX CORPORATION (US) 2009-07-16 US disclosed
US-20090181509-A1 POLYMER SEMICONDUCTORS WITH HIGH MOBILITY XEROX CORPORATION (US) 2009-07-16 US disclosed
US-20080102559-A1 Electronic devices XEROX CORPORATION 2008-05-01 US disclosed
US-20080103286-A1 Poly(dithienylbenzo[1,2-B:4,5-B']dithiophene) polymers XEROX CORPORATION 2008-05-01 US disclosed
EP-1916250-A1 Electronic devices comprising poly(dithienyl-benzodithiophenes) as semiconductors Xerox Corporation (US) 2008-04-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10158079-B2 Polymers of benzodithiophene and their use as organic semiconductors TST, TPST2, PPOX GPR35 4213/4885PTGS2 2370/4885ALOX5 1924/4885
US-20100121004-A1 PURIFICATION PROCESS FOR SEMICONDUCTING MONOMERS TERT, ADH1A, PCNA GPR35 3230/4885PTGS2 1854/4885ALOX5 881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.