Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470012 | 0.93 | ALDH1A1 (0.38) | ALDH1A1NUDT1MEN1KMT2AADORA3 | |
| SCHEMBL3836852 | 0.86 | ALDH1A1 (0.42) | ALDH1A1NUDT1MEN1KMT2AADORA3 | |
| SCHEMBL17797215 | 0.85 | RIPK1 (0.37) | ALDH1A1NUDT1MEN1KMT2ARORC | |
| SCHEMBL17797224 | 0.85 | NUDT1 (0.36) | ALDH1A1NUDT1MEN1KMT2AADORA3 | |
| SCHEMBL2464008 | 0.84 | NUDT1 (0.41) | ALDH1A1NUDT1MEN1KMT2AADORA3 | |
| SCHEMBL2469725 | 0.84 | ALDH1A1 (0.40) | ALDH1A1NUDT1ADORA3ALPLPDCD1LG2 | |
| SCHEMBL3841605 | 0.84 | KDM4E (0.37) | ALDH1A1NUDT1MEN1KMT2ARORC | |
| SCHEMBL2465259 | 0.83 | ALDH1A1 (0.34) | ALDH1A1NUDT1MEN1KMT2AADORA3 | |
| SCHEMBL17797246 | 0.82 | ALDH1A1 (0.36) | ALDH1A1NUDT1ADORA3RORCALPL | |
| SCHEMBL2465978 | 0.82 | ALDH1A1 (0.38) | ALDH1A1NUDT1ADORA3PDCD1LG2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | claimed |