Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4695319 | 0.75 | MAPK14 (0.42) | CCNA2CDK2MAPTKDM4EPTP4A3 | |
| SCHEMBL1180045 | 0.68 | MAPK1 (0.47) | ALDH1A1MAPTALOX15KDM4EGAA | |
| SCHEMBL23628970 | 0.68 | SMN1; SMN2 (0.54) | ALDH1A1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL21062055 | 0.67 | HCAR3 (0.46) | CCNA2CDK2ALDH1A1MAPTALOX15 | |
| SCHEMBL8142798 | 0.66 | CDK2 (0.42) | CCNA2CDK2ALDH1A1MAPTALOX15 | |
| SCHEMBL2744060 | 0.66 | L3MBTL1 (0.62) | CCNA2CDK2ALDH1A1MAPTKDM4E | |
| SCHEMBL17801297 | 0.65 | CYP1A2 (0.52) | ALDH1A1MAPTKDM4ENPC1HTT | |
| Bromide SCHEMBL2241396 | 0.65 | L3MBTL1 (0.60) | CCNA2CDK2ALDH1A1MAPTKDM4E | |
| SCHEMBL1425069 | 0.65 | ALOX15 (0.38) | ALDH1A1MAPTALOX15KDM4ESMN1; SMN2 | |
| SCHEMBL18358191 | 0.65 | KDM4E (0.49) | MAPTALOX15KDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227301-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience AG (DE) | 2017-10-11 | — | — | EP | disclosed |
| EP-2266981-B1 | Benzothiazole compounds useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2016-07-06 | — | — | EP | disclosed |
| WO-2016087417-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | WO | disclosed |