Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468053 | 0.77 | PDPK1 (0.57) | CYP2A6PDPK1LOXL2ADRB2SYK | |
| SCHEMBL14814093 | 0.77 | CYP2A6 (0.55) | CYP2A6PDPK1LOXL2ADRB2CHEK2 | |
| SCHEMBL19396075 | 0.77 | PDPK1 (0.47) | CYP2A6PDPK1LOXL2ADRB2CHEK2 | |
| SCHEMBL18670140 | 0.75 | TRPV4 (0.43) | CASP3TRPV4PIK3CAPI4KBPIK3CD | |
| SCHEMBL722198 | 0.74 | PDPK1 (0.77) | CYP2A6PDPK1LOXL2ADRB2CHEK2 | |
| SCHEMBL23832336 | 0.73 | CYP2A6 (0.55) | CYP2A6PDPK1LOXL2CASP3ADRB2 | |
| SCHEMBL30088436 | 0.73 | CYP2A6 (0.55) | CYP2A6PDPK1LOXL2CASP3ADRB2 | |
| SCHEMBL29462092 | 0.73 | CYP2A6 (0.59) | CYP2A6PDPK1LOXL2ADRB2CHEK2 | |
| SCHEMBL12490013 | 0.73 | CYP2A6 (0.59) | CYP2A6PDPK1LOXL2ADRB2CHEK2 | |
| SCHEMBL4021798 | 0.73 | LOXL2 (0.55) | CYP2A6PDPK1LOXL2ADRB2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10736320-B2 | Pesticidally active polycyclic derivatives with 5-membered sulfur containing heterocyclic ring systems | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-11 | — | — | US | disclosed |
| US-20180213784-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH 5-MEMBERED SULFUR CONTAINING HETEROCYCLIC RING SYSTEMS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-02 | — | — | US | disclosed |
| EP-3227301-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience AG (DE) | 2017-10-11 | — | — | EP | disclosed |
| EP-2970242-B1 | 3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH | NOVARTIS AG (CH) | 2017-09-06 | — | — | EP | disclosed |
| WO-2016087417-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180213784-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH 5-MEMBERED SULFUR CONTAINING HETEROCYCLIC RING SYSTEMS | DDT, TST, GSS | CYP2A6 1271/4885PDPK1 2899/4885LOXL2 3862/4885 |
| US-10736320-B2 | Pesticidally active polycyclic derivatives with 5-membered sulfur containing heterocyclic ring systems | DDT, TST, GSS | CYP2A6 1271/4885PDPK1 2899/4885LOXL2 3862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.