Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 3/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508788 | 0.78 | ST14 (0.48) | HRH3ALDH1A1CYP3A4TSHRST14 | |
| SCHEMBL1338455 | 0.76 | HRH3 (0.35) | HRH3ALDH1A1CYP3A4TSHRIDO1 | |
| SCHEMBL2163265 | 0.74 | ST14 (0.56) | HRH3ST14 | |
| SCHEMBL1846480 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL970450 | 0.74 | SMN1; SMN2 (0.45) | ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL1895592 | 0.74 | IDO1 (0.58) | ALDH1A1TP53CYP3A4ALOX15TSHR | |
| SCHEMBL120991 | 0.74 | LTA4H (0.54) | HRH3TSHR | |
| SCHEMBL15958746 | 0.72 | NQO1 (0.70) | HRH3ALDH1A1TSHRSMN1; SMN2NQO1 | |
| SCHEMBL1191309 | 0.72 | HRH3 (0.38) | HRH3NQO1APPIDO1 | |
| SCHEMBL19844431 | 0.70 | CA12 (0.50) | HRH3ALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016087593-A1 | NOVEL FUNGICIDAL QUINOLINYLAMIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | WO | disclosed |