Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | VHL | P40337 | 1/20 | 0.38 |
| ▸ | ELOC | Q15369 | 1/20 | 0.38 |
| ▸ | ELOB | Q15370 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5342317 | 0.78 | LTA4H (0.81) | LTA4HPPARGPPARATSHRPRSS1 | |
| SCHEMBL41775 | 0.76 | TSHR (0.67) | LTA4HPPARGPPARATSHRPRSS1 | |
| SCHEMBL15417600 | 0.76 | LTA4H (0.62) | LTA4HPPARGPPARATSHRPRSS1 | |
| SCHEMBL19579519 | 0.75 | LTA4H (0.50) | LTA4HPPARGPPARATSHRPRSS1 | |
| SCHEMBL728466 | 0.74 | LTA4H (0.54) | LTA4HPPARGPPARATSHRPRSS1 | |
| SCHEMBL970450 | 0.74 | SMN1; SMN2 (0.45) | TSHRCA2 | |
| SCHEMBL2163265 | 0.74 | ST14 (0.56) | HRH3 | |
| SCHEMBL11649743 | 0.74 | HRH3 (0.56) | LTA4HPPARGPPARATSHRPRSS1 | |
| SCHEMBL17801433 | 0.74 | HRH3 (0.39) | TSHRHRH3 | |
| SCHEMBL6278014 | 0.74 | LTA4H (0.54) | LTA4HPPARGPPARATSHRPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200440-B1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | CRESTONE INC (US) | 2017-07-19 | — | — | EP | claimed |
| US-8148380-B2 | Antibacterial amide and sulfonamide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-04-03 | — | — | US | claimed |
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | CRESTONE, INC. (US) | 2012-01-19 | — | — | US | claimed |
| EP-2200440-A1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | Crestone, Inc. (US) | 2010-06-30 | — | — | EP | claimed |
| WO-2009015208-A1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | REPLIDYNE, INC. (US) | 2009-01-29 | — | — | WO | claimed |
| EP-0241363-B1 | NUCLEOSIDE DERIVATIVES AND THEIR USE IN THE SYNTHESIS OF OLIGONUCLEOTIDES | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1991-09-25 | — | — | EP | claimed |
| EP-0241363-A1 | Nucleoside derivatives and their use in the synthesis of oligonucleotides | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1987-10-14 | — | — | EP | claimed |
| JP-6263795-A | — | — | None | — | — | JP | disclosed |
| JP-2101099-A | — | — | None | — | — | JP | disclosed |
| US-11650499-B2 | Photosensitive resin composition, organic EL element barrier rib, and organic EL element | SHOWA DENKO K.K. (JP) | 2023-05-16 | — | — | US | disclosed |
| CN-110573240-B | Selectively permeable graphene oxide membranes | 日东电工株式会社 | 2022-11-22 | — | — | CN | disclosed |
| CN-113861268-A | Cell penetrating peptides and methods of making and using the same | 恩特拉达治疗学股份有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-106852146-B | Cell penetrating peptides and methods of making and using the same | 恩特拉达治疗学股份有限公司 | 2021-08-13 | — | — | CN | disclosed |
| EP-0467701-A2 | Cyclic HIV principal neutralizing determinant peptides | MERCK & CO. INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0467700-A2 | Coconjugate vaccines comprising immunogenic protein, HIV related peptides, and anionic moieties | MERCK & CO. INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0467699-A2 | Cyclic HIV principal neutralizing determinant peptides | MERCK & CO. INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0452257-A2 | Novel platelet-aggregation inhibitors | CIBA-GEIGY AG (CH) | 1991-10-16 | — | — | EP | disclosed |
| EP-0394194-A1 | Protected amino-acids and process for their preparation | CALBIOCHEM-NOVABIOCHEM AG (CH) | 1990-10-24 | — | — | EP | disclosed |
| JP-H02101099-A | PEPTIDE | NIPPON CHEMIPHAR CO LTD | 1990-04-12 | — | — | JP | disclosed |
| EP-0356395-A2 | Flanking peptides and process for their preparation | CIBA-GEIGY AG (CH) | 1990-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015941-A1 | Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds | NAAA, AADAC, RPSA | LTA4H 3291/4885PPARG 987/4885PPARA 436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.