SCHEMBL1780263

SCHEMBL1780263

O=C1C(Cl)=CC(=Nc2ccc(O)cc2Cl)C=C1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.39
TTR P02766 2/20 0.35
BACE1 P56817 2/20 0.35
ESR1 P03372 6/20 0.33
ESR2 Q92731 4/20 0.33
MAOA P21397 1/20 0.33
UGT1A1 P22309 1/20 0.33
MAOB P27338 1/20 0.33
NSD2 O96028 1/20 0.33
MMP14 P50281 1/20 0.33
CASP6 P55212 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
RNASEL Q05823 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL107238 0.75 TXNRD1 (0.37) ESR1ESR2CA12CA1CA2
SCHEMBL505621 0.74 TXNRD1 (0.36) ESR1ESR2CA12CA1CA2
Water SCHEMBL3454312 0.72 TXNRD1 (0.35) ESR1ESR2CA12CA1CA2
Water SCHEMBL28299335 0.72 TXNRD1 (0.35) ESR1ESR2CA12CA1CA2
SCHEMBL11405796 0.71 RNASEL (0.38) HSD17B10TTRBACE1ESR1ESR2
SCHEMBL9077264 0.70 HSD17B10 (0.52) HSD17B10TTRBACE1ESR1ESR2
SCHEMBL3132789 0.70 PTGS1 (0.46) HSD17B10ESR1ESR2CA1CA2
SCHEMBL8954156 0.69 PTGS1 (0.45) HSD17B10ESR1ESR2CA1CA2
SCHEMBL11315992 0.66 CA12 (0.33) HSD17B10BACE1ESR1ESR2CA12
SCHEMBL13525191 0.66 HSD17B10 (0.35) HSD17B10TTRBACE1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4375398-A1 CARBON DIOXIDE RECOVERY SYSTEM Chiyoda Corporation (JP) 2024-05-29 EP disclosed
WO-2024070011-A1 LIQUID FUEL PRODUCTION SYSTEM AND METHOD FOR PRODUCING LIQUID FUEL 千代田化工建設株式会社 2024-04-04 WO disclosed
WO-2023003029-A1 CARBON DIOXIDE RECOVERY SYSTEM 千代田化工建設株式会社 2023-01-26 WO disclosed
US-20140024102-A1 MICROBIAL FUEL CELL, FUEL AND MICROBES FOR SAID FUEL CELL, BIOREACTOR AND BIOSENSOR SONY CORPORATION 2014-01-23 US disclosed
US-8338039-B2 Fuel cell SONY CORPORATION (JP) 2012-12-25 US disclosed
US-20110287312-A1 BIOFUEL CELL SONY CORPORATION (JP) 2011-11-24 US disclosed
US-20110250511-A1 BIOFUEL CELL SONY CORPORATION (JP) 2011-10-13 US disclosed
US-20110143223-A1 FUEL CELL SONY CORPORATION (JP) 2011-06-16 US disclosed
US-20110117453-A1 FUEL REFORMER AND POWER GENERATION APPARATUS USING THE SAME SONY CORPORATION (JP) 2011-05-19 US disclosed