Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 2/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 9/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 9/20 | 0.34 |
| ▸ | IGF1R | P08069 | 3/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1778749 | 0.92 | INSR (0.35) | PDE7AF10INSRALKIGF1R | |
| SCHEMBL1778250 | 0.89 | AURKA (0.45) | PDE7AINSRALKIGF1RAURKA | |
| SCHEMBL1780565 | 0.86 | ALDH1A1 (0.40) | STING1KDM4ELMNA | |
| SCHEMBL1778870 | 0.86 | CSF1R (0.40) | WDR5PDE7AINSRALKIGF1R | |
| SCHEMBL1779266 | 0.86 | WDR5 (0.37) | WDR5INSRALKIGF1RAURKA | |
| SCHEMBL1777250 | 0.86 | IGF1R (0.44) | WDR5PDE7AINSRALKIGF1R | |
| SCHEMBL1781437 | 0.85 | BTK (0.45) | INSRALKIGF1RAURKABTK | |
| SCHEMBL1777894 | 0.85 | ALK (0.43) | WDR5PDE7AINSRALKIGF1R | |
| SCHEMBL1777877 | 0.84 | PDE7A (0.43) | WDR5PDE7AINSRALKIGF1R | |
| SCHEMBL1781045 | 0.82 | SIRT6 (0.42) | WDR5PDE7ABTKLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904503-B1 | 1H-THIENO[2,3-C]-PYRAZOLE COMPOUNDS USEFUL AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2013-11-06 | — | — | EP | disclosed |
| US-7943654-B2 | 1H-thieno[2,3-c]pyrazole compounds useful as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2011-05-17 | — | — | US | disclosed |
| US-20090149457-A1 | 1H-Thieno[2,3-c]Pyrazole Compounds Useful as Kinase Inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-06-11 | — | — | US | disclosed |
| EP-1904503-A1 | 1H-THIENO[2,3-C]-PYRAZOLE COMPOUNDS USEFUL AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007009898-A1 | 1H-THIENO[2,3-C]PYRAZOLE COMPOUNDS USEFUL AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2007-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149457-A1 | 1H-Thieno[2,3-c]Pyrazole Compounds Useful as Kinase Inhibitors | CCNH, PDK1, MAP3K5 | WDR5 1060/4885STING1 4621/4885PDE7A 2291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.