Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28165649 | 0.89 | ALDH1A1 (0.43) | LMNATSHRHPGDALDH1A1MAPT | |
| SCHEMBL13280139 | 0.86 | KMT2A (0.43) | LMNATSHRHPGDALDH1A1MAPT | |
| SCHEMBL18830371 | 0.85 | ALDH1A1 (0.36) | LMNATSHRHPGDALDH1A1MAPT | |
| SCHEMBL18829979 | 0.80 | LMNA (0.47) | LMNATSHRHPGDALDH1A1MAPT | |
| SCHEMBL13467799 | 0.72 | EZH2 (0.64) | — | |
| SCHEMBL13279927 | 0.71 | ALDH1A1 (0.47) | LMNATSHRHPGDALDH1A1MAPT | |
| SCHEMBL13280243 | 0.70 | ALDH1A1 (0.46) | LMNATSHRHPGDALDH1A1MAPT | |
| SCHEMBL18829835 | 0.70 | LMNA (0.42) | LMNATSHRHPGDALDH1A1MAPT | |
| SCHEMBL13468019 | 0.69 | LMNA (0.39) | LMNATSHRHPGDALDH1A1MAPT | |
| SCHEMBL28814162 | 0.69 | KMT2A (0.54) | LMNATSHRHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697198-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2016-06-08 | — | — | EP | disclosed |