Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | TCF4 | P15884 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17804319 | 0.87 | L3MBTL1 (0.41) | DHODHL3MBTL1HPGDFBP1TSHR | |
| SCHEMBL17804328 | 0.82 | CYP1A2 (0.41) | TCF4CTNNB1L3MBTL1HPGDFBP1 | |
| SCHEMBL2080107 | 0.81 | ALDH1A1 (0.52) | L3MBTL1HPGDTSHRALDH1A1TDP1 | |
| SCHEMBL13468191 | 0.80 | DHODH (0.52) | DHODHHPGDTSHRALDH1A1 | |
| SCHEMBL27183608 | 0.80 | DHODH (0.49) | DHODHHPGDTSHRALDH1A1TDP1 | |
| SCHEMBL31636358 | 0.80 | TSHR (0.56) | DHODHL3MBTL1HPGDFBP1TSHR | |
| SCHEMBL2049036 | 0.80 | TSHR (0.56) | DHODHL3MBTL1HPGDFBP1TSHR | |
| SCHEMBL2043408 | 0.77 | MEN1 (0.50) | DHODHHPGDTDP1SMN1; SMN2 | |
| SCHEMBL11220359 | 0.77 | VCAM1 (0.43) | L3MBTL1HPGDALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL15870998 | 0.76 | HPGD (0.53) | TCF4CTNNB1HPGDTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697198-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2016-06-08 | — | — | EP | disclosed |