Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271485 | 0.88 | VCAM1 (0.44) | VCAM1POLBALDH1A1GAAHPGD | |
| SCHEMBL11231775 | 0.82 | LMNA (0.42) | ALDH1A1HPGDPDGFRBFGFR1PDGFRA | |
| SCHEMBL19239521 | 0.81 | PDGFRB (0.45) | VCAM1POLBALDH1A1HPGDPDGFRB | |
| SCHEMBL11208114 | 0.80 | HCAR3 (0.47) | POLBALDH1A1HPGDPDGFRBFGFR1 | |
| SCHEMBL5115680 | 0.80 | TSHR (0.51) | VCAM1ALDH1A1GAAHPGDMAPT | |
| SCHEMBL10487718 | 0.79 | POLB (0.57) | POLBALDH1A1GAAHPGDPDGFRB | |
| SCHEMBL11279686 | 0.79 | HCAR3 (0.52) | POLBALDH1A1HPGDPDGFRBFGFR1 | |
| SCHEMBL10487709 | 0.79 | POLB (0.48) | POLBALDH1A1HPGDPDGFRBFGFR1 | |
| SCHEMBL11219158 | 0.78 | VCAM1 (0.64) | VCAM1ALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL17804346 | 0.77 | DHODH (0.44) | ALDH1A1HPGDRECQLL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344957-A | Benz-acyl-benzimidazole derivatives and antiallergic compositions | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| EP-0000574-B1 | BENZIMIDAZOLE-2 DERIVATIVES, THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF MEDICAMENTS | CIBA-GEIGY AG (CH) | 1982-08-04 | — | — | EP | disclosed |
| US-4323688-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1982-04-06 | — | — | US | disclosed |
| US-4322431-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0014469-A2 | Benzimidazole-2-yl derivatives as medicines, their application and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1980-08-20 | — | — | EP | disclosed |
| US-4213993-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| US-4141982-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |
| EP-0000574-A1 | Benzimidazole-2 derivatives, their preparation and their use for the preparation of medicaments | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |