Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24383692 | 0.74 | ALDH1A1 (0.49) | NPSR1GAATSHRSMN1; SMN2MAPK1 | |
| SCHEMBL5716237 | 0.71 | DRD2 (0.47) | NPSR1GAATSHRSMN1; SMN2MAPK1 | |
| SCHEMBL2090488 | 0.71 | TSHR (0.40) | NPSR1TSHRSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5716359 | 0.70 | NPSR1 (0.49) | NPSR1GAATSHRSMN1; SMN2MAPK1 | |
| SCHEMBL4468998 | 0.69 | ADRB1 (0.51) | TSHRALDH1A1MAPT | |
| SCHEMBL5542946 | 0.69 | LMNA (0.55) | NPSR1GAATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL5543471 | 0.69 | MAPK1 (0.51) | NPSR1GAATSHRMAPK1ALDH1A1 | |
| SCHEMBL12176173 | 0.68 | GAA (0.47) | NPSR1GAATSHRMAPK1ALDH1A1 | |
| SCHEMBL2937385 | 0.68 | KEAP1 (0.42) | NPSR1GAATSHRSMN1; SMN2MAPK1 | |
| SCHEMBL147644 | 0.68 | TSHR (0.38) | GAATSHRSMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2381778-B1 | C5AR ANTAGONISTS | CHEMOCENTRYX INC (US) | 2016-06-08 | — | — | EP | disclosed |