SCHEMBL17808017

SCHEMBL17808017

c1ccc(-c2cccc(-c3cc(-c4cccc(-c5cccnc5)c4)nc(-c4cc5ccccc5c5ccccc45)n3)c2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 6/20 0.62
CYP19A1 P11511 2/20 0.50
KMO O15229 1/20 0.47
CYP11B2 P19099 5/20 0.47
CYP17A1 P05093 1/20 0.47
DHODH Q02127 1/20 0.46
GPR84 Q9NQS5 1/20 0.46
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CYP2C9 P11712 3/20 0.41
MKNK1 Q9BUB5 2/20 0.41
MKNK2 Q9HBH9 2/20 0.41
MEN1 O00255 1/20 0.41
PSIP1 O75475 1/20 0.41
AXL P30530 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21317598 0.97 CYP11B1 (0.59) CYP11B1CYP19A1KMOCYP11B2CYP17A1
SCHEMBL17808040 0.95 CYP11B1 (0.67) CYP11B1CYP19A1KMOCYP11B2CYP17A1
SCHEMBL22461620 0.95 CYP11B1 (0.62) CYP11B1CYP19A1KMOCYP11B2CYP17A1
SCHEMBL17808043 0.92 CYP11B1 (0.63) CYP11B1CYP19A1KMOCYP11B2CYP17A1
SCHEMBL21725403 0.92 CYP11B1 (0.66) CYP11B1CYP19A1CYP11B2CYP17A1DHODH
SCHEMBL19638272 0.92 CYP11B1 (0.66) CYP11B1CYP19A1CYP11B2CYP17A1DHODH
SCHEMBL17918031 0.92 CYP11B1 (0.58) CYP11B1CYP19A1CYP11B2CYP17A1DHODH
SCHEMBL21725390 0.91 CYP11B1 (0.58) CYP11B1CYP19A1KMOCYP11B2CYP17A1
SCHEMBL17917875 0.91 CYP11B1 (0.58) CYP11B1CYP19A1KMOCYP11B2CYP17A1
SCHEMBL17917880 0.91 CYP11B1 (0.61) CYP11B1CYP19A1CYP11B2CYP17A1DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3309235-B1 ORGANIC LIGHT EMITTING ELEMENT HAVING HIGH EFFICIENCY SFC CO LTD (KR) 2023-10-18 EP disclosed
EP-3244464-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-02-23 EP disclosed
US-11158811-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-10-26 US disclosed
US-10950802-B2 Organic light-emitting diode with high efficiency SFC CO., LTD. (KR) 2021-03-16 US disclosed
US-20200303658-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2020-09-24 US disclosed
US-10593884-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-03-17 US disclosed
US-10559759-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-02-11 US disclosed
US-20190273216-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2019-09-05 US disclosed
US-10276800-B2 Organic electroluminescence device having at least an a node, a hole injection layer, a first hole transport layer. A second hole transport layer a luminous layer, an electron transport layer, and a cathode HODOGAYA CHEMICAL CO., LTD. (JP) 2019-04-30 US disclosed
US-20190006596-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2019-01-03 US disclosed
EP-3244464-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
EP-3244463-A1 ORGANIC ELECTROLUMINESCENT DEVICE Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
US-20170317291-A1 ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-11-02 US disclosed
EP-3240057-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-01 EP disclosed
EP-3229284-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-10-11 EP disclosed
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-06-29 US disclosed
EP-3156402-A1 PYRIMIDINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-04-19 EP disclosed
WO-2016111254-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-07-14 WO disclosed
WO-2016088759-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10276800-B2 Organic electroluminescence device having at least an a node, a hole injection layer, a first hole transport layer. A second hole transport layer a luminous layer, an electron transport layer, and a cathode SLC29A1, SLC29A2, NUDT1 CYP11B1 1848/4885CYP19A1 1602/4885KMO 1176/4885
US-10593884-B2 Organic electroluminescent device AHR, SLC18A1, KCNH1 CYP11B1 272/4885CYP19A1 42/4885KMO 631/4885
US-20170186967-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE TYMS, UMPS, DPYD CYP11B1 1800/4885CYP19A1 1535/4885KMO 1276/4885
US-20200303658-A1 PYRIMIDINE DERIVATIVE AND AN ORGANIC ELECTROLUMINESCENT DEVICE TYMS, UMPS, DPYD CYP11B1 1800/4885CYP19A1 1535/4885KMO 1276/4885
US-20190006596-A1 ORGANIC ELECTROLUMINESCENT DEVICE SLC43A1, SLC7A5, SLCO4C1 CYP11B1 1290/4885CYP19A1 283/4885KMO 527/4885
US-10559759-B2 Organic electroluminescent device SLC29A2, SLC29A1, SLCO4C1 CYP11B1 1190/4885CYP19A1 1008/4885KMO 556/4885
US-20170317291-A1 ORGANIC ELECTROLUMINESCENCE DEVICE NUDT1, SLCO4C1, SLC7A5 CYP11B1 1637/4885CYP19A1 1533/4885KMO 703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.