Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.32 |
| ▸ | KDM4A | O75164 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.32 |
| ▸ | TET3 | O43151 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17449733 | 0.80 | ALDH1A1 (0.36) | OTCKMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL20431156 | 0.78 | ALDH1A1 (0.31) | OTCALDH1A1 | |
| SCHEMBL20307714 | 0.76 | GPR84 (0.50) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL17932835 | 0.74 | CASP2 (0.53) | — | |
| SCHEMBL17932834 | 0.74 | CASP2 (0.53) | — | |
| SCHEMBL24779309 | 0.73 | CA5B (0.39) | KMT2ASMN1; SMN2ALDH1A1MEN1TP53 | |
| SCHEMBL3347293 | 0.72 | GPR84 (0.45) | OTCGPR84FFAR1DDAH1TET2 | |
| SCHEMBL3346616 | 0.72 | GPR84 (0.45) | OTCGPR84FFAR1DDAH1TET2 | |
| SCHEMBL18125979 | 0.72 | GPR84 (0.48) | OTCGPR84FFAR1TET2KDM4A | |
| SCHEMBL23152933 | 0.71 | ALB (0.35) | NOD1KMT2ASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016148674-A1 | CONJUGATES FOR TREATING DISEASES | ENDOCYTE, INC. (US) | 2016-09-22 | — | — | WO | disclosed |
| WO-2016089879-A1 | CONJUGATES OF GARFTASE INHIBITORS | ENDOCYTE, INC. (US) | 2016-06-09 | — | — | WO | disclosed |