Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26690735 | 0.85 | KMT2A (0.45) | PKMKMT2ANR3C2LMNASMN1; SMN2 | |
| SCHEMBL22637693 | 0.84 | KMT2A (0.46) | PKMKMT2ANR3C2LMNASMN1; SMN2 | |
| SCHEMBL22637999 | 0.81 | HCAR3 (0.43) | PKMKMT2ANR3C2LMNASMN1; SMN2 | |
| SCHEMBL17437926 | 0.78 | HCAR3 (0.41) | PKMKMT2ANR3C2SMN1; SMN2HCAR3 | |
| SCHEMBL17813610 | 0.75 | PDK1 (0.35) | KMT2AHCAR3CTSKMEN1OPRK1 | |
| SCHEMBL14335305 | 0.73 | NR3C2 (0.48) | PKMKMT2ANR3C2LMNASMN1; SMN2 | |
| SCHEMBL22320386 | 0.72 | HSD11B1 (0.41) | PKMKMT2ANR3C2SMN1; SMN2PIK3CD | |
| SCHEMBL26416283 | 0.72 | NR3C2 (0.49) | PKMKMT2ANR3C2LMNASMN1; SMN2 | |
| SCHEMBL26416280 | 0.72 | PKM (0.47) | PKMKMT2ANR3C2LMNASMN1; SMN2 | |
| SCHEMBL23293380 | 0.71 | PDK2 (0.35) | PKMKMT2ANR3C2SMN1; SMN2HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016088813-A1 | NOVEL DIAZABICYCLO[2.2.2]OCTANE DERIVATIVE | 持田製薬株式会社 | 2016-06-09 | — | — | WO | disclosed |