SCHEMBL1781545

SCHEMBL1781545

O=C(Nc1ccco1)c1ccco1

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.65
PTPN2 P17706 1/20 0.62
PTPN1 P18031 1/20 0.62
PTPN6 P29350 1/20 0.62
PTPN11 Q06124 1/20 0.62
SMN1; SMN2 Q16637 6/20 0.59
NPC1 O15118 4/20 0.59
TP53 P04637 2/20 0.59
ALDH1A1 P00352 2/20 0.59
GAA P10253 1/20 0.59
KMT2A Q03164 4/20 0.57
MAPT P10636 3/20 0.57
MEN1 O00255 2/20 0.57
ESR2 Q92731 1/20 0.57
GFER P55789 1/20 0.57
CYP1A2 P05177 1/20 0.56
ATM Q13315 1/20 0.54
PKM P14618 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8702006 0.79 CES2 (0.62) RAB9APTPN2PTPN1PTPN6PTPN11
SCHEMBL9547521 0.79 SMN1; SMN2 (0.56) RAB9APTPN2PTPN1PTPN6PTPN11
SCHEMBL2997673 0.78 RAB9A (1.00) RAB9APTPN2PTPN1PTPN6PTPN11
SCHEMBL18920602 0.78 SMN1; SMN2 (0.72) RAB9APTPN1SMN1; SMN2NPC1TP53
SCHEMBL23011774 0.77 ALDH1A1 (0.84) RAB9APTPN2PTPN1PTPN6PTPN11
Hydrochloric Acid SCHEMBL31228945 0.77 RAB9A (0.96) RAB9APTPN2PTPN1PTPN6PTPN11
SCHEMBL7108252 0.77
SCHEMBL3483318 0.77
SCHEMBL1520253 0.77 KMT2A (0.67) RAB9APTPN2PTPN1PTPN6PTPN11
SCHEMBL9538774 0.76 RAB9A (0.69) RAB9APTPN2PTPN1PTPN6PTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220218639-A1 TUNEABLE DELIVERY OF NANOPARTICLE BOUND ACTIVE PLASMIN FOR THE TREATMENT OF THROMBOSIS INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION 2022-07-14 US claimed
US-20110118127-A1 MARKER GENES FOR SCREENING OF DRUG-INDUCED TOXICITY IN HUMAN CELLS AND SCREENING METHOD USING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2011-05-19 US claimed
EP-1226238-A2 METHOD FOR CREATING DIVERGENT POPULATIONS OF NUCLEIC ACID MOLECULES AND PROTEINS Cytos Biotechnology AG (CH) 2002-07-31 EP claimed
WO-2001030989-A2 METHOD FOR CREATING DIVERGENT POPULATIONS OF NUCLEIC ACID MOLECULES AND PROTEINS CYTOS BIOTECHNOLOGY AG (US) 2001-05-03 WO claimed
EP-4219735-B1 METHOD AND APPARATUS FOR ANALYTE DETECTION USING AN ELECTROCHEMICAL BIOSENSOR ABBOTT DIABETES CARE (US) 2026-04-01 EP disclosed
US-20250312524-A1 METHODS OF AMELIORATION OF CEREBROSPINAL FLUID AND DEVICES AND SYSTEMS THEREFOR ENCLEAR THERAPIES, INC. 2025-10-09 US disclosed
US-12350416-B2 Methods of amelioration of cerebrospinal fluid and devices and systems therefor ENCLEAR THERAPIES, INC. (US) 2025-07-08 US disclosed
US-12331108-B2 Antibodies with functional domains in the elbow region between variable and constant domain INSTITUTE FOR RESEARCH IN BIOMEDICINE (CH) 2025-06-17 US disclosed
EP-4538692-A2 METHOD AND APPARATUS FOR ANALYTE DETECTION USING AN ELECTROCHEMICAL BIOSENSOR Abbott Diabetes Care (US) 2025-04-16 EP disclosed
EP-4219735-A1 METHOD AND APPARATUS FOR ANALYTE DETECTION USING AN ELECTROCHEMICAL BIOSENSOR Abbott Diabetes Care (US) 2023-08-02 EP disclosed
CN-116059379-A Compositions and methods utilizing STAT1/3 inhibitors and oncolytic herpes viruses 复诺健生物科技加拿大有限公司 2023-05-05 CN disclosed
EP-3645733-B1 METHOD AND APPARATUS FOR ANALYTE DETECTION USING AN ELECTROCHEMICAL BIOSENSOR ABBOTT DIABETES CARE (US) 2023-04-26 EP disclosed
US-4569842-A ANTIINFLAMMATORY, -TUMOR, PYRETICS-LIPEMIC AGENTS; ANALGESICS; HYPOGLYCEMIC AND HYPOTENSIVE AGENTS KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-02-11 US disclosed
US-4559327-A HYPOGLYLCEMIC, ANTIINFLAMMORY AGENTS; HYPERLIPEMIA, ANTIPYRETICS, ANTITUMOR AGENTS KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-12-17 US disclosed
US-4555505-A Method for the treatment of hyperglycemia using p-aminobenzoate-N-L-rhamnoside KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-11-26 US disclosed
US-4440757-A SUGAR SUBSTITUTED AMINOBENZOIC ACIDS KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-04-03 US disclosed
US-4322408-A HYPOTENSIVE, HYPOGLYCEMIC, ANTITUMOR, ANTILIPEMIC AND ANTIINFLAMMATORY AGENTS KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1982-03-30 US disclosed
US-4322409-A HYPOTENSIVE, HYPOGLYCEMIC, ANTITUMOR, ANTILIPEMIC AND ANTIINFLAMMATORY AGENTS KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1982-03-30 US disclosed
US-4315921-A TREATMENT OF HYDERTENSION KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1982-02-16 US disclosed
US-4313939-A Pharmaceutical composition containing para-aminobenzoic acid-N-L-rhamnoside as an active ingredient KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1982-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220218639-A1 TUNEABLE DELIVERY OF NANOPARTICLE BOUND ACTIVE PLASMIN FOR THE TREATMENT OF THROMBOSIS PLAT, PLG, PLAUR RAB9A 1872/4885PTPN2 1906/4885PTPN1 1663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.