Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.97 |
| ▸ | POLB | P06746 | 2/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | MLNR | O43193 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL981894 | 0.84 | KDM4E (0.74) | ATML3MBTL1MAPK1POLBKDM4E | |
| SCHEMBL981898 | 0.83 | KDM4E (1.00) | ATML3MBTL1MAPK1POLBKDM4E | |
| SCHEMBL3975423 | 0.79 | KDM4E (0.69) | ATML3MBTL1MAPK1POLBKDM4E | |
| SCHEMBL13844736 | 0.78 | KDM4E (0.73) | ATML3MBTL1MAPK1POLBKDM4E | |
| SCHEMBL982631 | 0.77 | KDM4E (0.71) | ATML3MBTL1MAPK1POLBKDM4E | |
| SCHEMBL980644 | 0.76 | KDM4E (0.69) | ATML3MBTL1MAPK1POLBKDM4E | |
| SCHEMBL3976738 | 0.76 | KDM4E (0.65) | ATML3MBTL1MAPK1POLBKDM4E | |
| SCHEMBL5370477 | 0.74 | TSHR (0.71) | ATML3MBTL1MAPK1POLBKDM4E | |
| SCHEMBL28566828 | 0.73 | TSHR (0.58) | ATML3MBTL1MAPK1POLBKDM4E | |
| SCHEMBL5372898 | 0.73 | SMN1; SMN2 (0.71) | ATML3MBTL1MAPK1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094226-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GLYCOREGIMMUNE, INC. (US) | 2016-06-16 | — | — | WO | disclosed |
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | ALTIUM GROWTH FUND, LP | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | RXRA, RXRG, CX3CR1 | ATM 4490/4885L3MBTL1 3605/4885MAPK1 2188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.