Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3273189 | 0.76 | MAOA (0.37) | ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL339008 | 0.72 | TP53 (0.43) | ALDH1A1MAPTESR1ESR2 | |
| SCHEMBL716719 | 0.71 | MEN1 (0.33) | DRD2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL31299941 | 0.71 | TP53 (0.41) | ALDH1A1MAPTESR1ESR2 | |
| SCHEMBL6382158 | 0.70 | ALDH1A1 (0.40) | MEN1ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL27845453 | 0.69 | MEN1 (0.33) | MEN1ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL7939919 | 0.69 | MAPT (0.39) | DRD2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL16334142 | 0.69 | MEN1 (0.33) | MEN1ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7930856 | 0.69 | DRD2 (0.30) | DRD2 | |
| SCHEMBL30122516 | 0.69 | ALDH1A1 (0.39) | MEN1ALDH1A1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860149-B1 | PROPYLENE POLYMER COMPOSITION, USE THEREOF, AND PROCESS FOR PRODUCTION OF THERMOPLASTIC POLYMER COMPOSITION | MITSUI CHEMICALS INC (JP) | 2016-06-15 | — | — | EP | disclosed |