Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.69 |
| ▸ | MPO | P05164 | 10/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.67 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.67 |
| ▸ | HTR6 | P50406 | 3/20 | 0.66 |
| ▸ | HTR1A | P08908 | 3/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30275112 | 1.00 | HTR2A (0.69) | HTR2AMPOSLC6A4GPR84HTR6 | |
| SCHEMBL11992509 | 0.87 | MPO (0.78) | HTR2AMPOSLC6A4GPR84HTR6 | |
| SCHEMBL1969257 | 0.86 | HTR6 (0.62) | HTR2AMPOSLC6A4GPR84HTR6 | |
| Hydrochloric Acid SCHEMBL21546035 | 0.86 | MPO (0.76) | HTR2AMPOSLC6A4GPR84HTR6 | |
| SCHEMBL7671849 | 0.83 | HTR2A (0.60) | HTR2AMPOSLC6A4GPR84HTR6 | |
| SCHEMBL4496642 | 0.81 | HTR2A (0.71) | HTR2AMPOSLC6A4GPR84HTR6 | |
| SCHEMBL743153 | 0.81 | HTR2A (1.00) | HTR2AMPOSLC6A4GPR84HTR6 | |
| SCHEMBL31535627 | 0.81 | HTR2A (0.71) | HTR2AMPOSLC6A4GPR84HTR6 | |
| SCHEMBL7710633 | 0.81 | HTR2A (0.71) | HTR2AMPOSLC6A4GPR84HTR6 | |
| SCHEMBL30952647 | 0.81 | HTR2A (1.00) | HTR2AMPOSLC6A4GPR84HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230265-A1 | A PROCESS FOR THE MANUFACTURE OF IDALOPIRDINE | H. Lundbeck A/S (DK) | 2017-10-18 | — | — | EP | disclosed |
| US-20160168089-A1 | PROCESS FOR THE MANUFACTURE OF IDALOPIRDINE | LUNDBECK A/S (DK) | 2016-06-16 | — | — | US | disclosed |
| WO-2016091997-A1 | A PROCESS FOR THE MANUFACTURE OF IDALOPIRDINE | H. LUNDBECK A/S (DK) | 2016-06-16 | — | — | WO | disclosed |
| WO-2016091997-A1 | A PROCESS FOR THE MANUFACTURE OF IDALOPIRDINE | H. LUNDBECK A/S (DK) | 2016-06-16 | — | — | WO | disclosed |
| US-20160168089-A1 | PROCESS FOR THE MANUFACTURE OF IDALOPIRDINE | LUNDBECK A/S (DK) | 2016-06-16 | — | — | US | disclosed |
| US-20160168089-A1 | PROCESS FOR THE MANUFACTURE OF IDALOPIRDINE | LUNDBECK A/S (DK) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168089-A1 | PROCESS FOR THE MANUFACTURE OF IDALOPIRDINE | ADRA2C, QDPR, ADRA1D | HTR2A 110/4885MPO 2341/4885SLC6A4 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.