SCHEMBL17822288

SCHEMBL17822288

CCSC(C)(SCC)C(=O)OC

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.38
TSHR P16473 1/20 0.31
KCNN4 O15554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13313610 0.81 DGAT1 (0.38) DGAT1TSHRKCNN4
SCHEMBL9161041 0.77 DGAT1 (0.35) DGAT1
SCHEMBL10924273 0.72 TSHR (0.38) TSHR
SCHEMBL22118475 0.71 ALDH1A1 (0.31) DGAT1
SCHEMBL2475483 0.69 DGAT1 (0.44) DGAT1TSHRKCNN4
SCHEMBL15816807 0.68
SCHEMBL17280883 0.68 DGAT1 (0.35) DGAT1TSHR
SCHEMBL2327259 0.67 DGAT1 (0.42) DGAT1TSHRKCNN4
SCHEMBL47401 0.67
Propionic Acid SCHEMBL8734813 0.67 FFAR3 (0.48) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10188718-B2 Vaccines against Streptococcus pneumoniae serotype 4 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2019-01-29 US disclosed
EP-3230297-B1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 MAX PLANCK GESELLSCHAFT (DE) 2018-10-17 EP disclosed
US-20170333545-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2017-11-23 US disclosed
US-20170333545-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2017-11-23 US disclosed
EP-3230297-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2017-10-18 EP disclosed
WO-2016091399-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-06-16 WO disclosed
WO-2016091399-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170333545-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 NEU4, PA2G4, STT3B DGAT1 2787/4885TSHR 2834/4885KCNN4 3536/4885
US-10188718-B2 Vaccines against Streptococcus pneumoniae serotype 4 NEU4, PA2G4, STT3B DGAT1 2787/4885TSHR 2834/4885KCNN4 3536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.