Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | TK1 | P04183 | 3/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10239442 | 0.83 | DHFR (0.60) | DHFRTK1 | |
| SCHEMBL17826619 | 0.79 | DHFR (0.49) | DHFRTK1 | |
| SCHEMBL8745678 | 0.78 | TK1 (0.52) | DHFRTK1TYMP | |
| SCHEMBL8827975 | 0.78 | TK1 (0.52) | DHFRTK1TYMP | |
| SCHEMBL16158818 | 0.77 | TDP1 (0.34) | — | |
| SCHEMBL17826624 | 0.76 | DHFR (0.53) | DHFRTK1 | |
| SCHEMBL17826617 | 0.76 | DHFR (0.44) | DHFRTK1TYMP | |
| SCHEMBL5982146 | 0.70 | ALDH1A1 (0.49) | DHFRTK1TYMP | |
| SCHEMBL9218555 | 0.70 | ALDH1A1 (0.49) | DHFRTK1TYMP | |
| SCHEMBL25701920 | 0.69 | TK1 (0.55) | DHFRTK1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365605-B2 | Cyclic nucleotide analogs | ALIOS BIOPHARMA, INC. (US) | 2016-06-14 | — | — | US | disclosed |