Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.44 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11673199 | 0.85 | ALDH1A1 (0.53) | TLR2ERN1TLR1TLR6MCHR1 | |
| SCHEMBL5483924 | 0.83 | ERN1 (0.58) | TLR2ERN1TLR1TLR6MCHR1 | |
| SCHEMBL17828382 | 0.83 | MCHR1 (0.41) | TLR2ERN1TLR1TLR6MCHR1 | |
| SCHEMBL20818485 | 0.76 | ALDH1A1 (0.50) | TLR2ERN1TLR1TLR6ALDH1A1 | |
| SCHEMBL738533 | 0.75 | ERN1 (0.66) | TLR2ERN1TLR1TLR6ALDH1A1 | |
| SCHEMBL29954368 | 0.75 | ERN1 (0.66) | TLR2ERN1TLR1TLR6ALDH1A1 | |
| SCHEMBL6468006 | 0.75 | ERN1 (0.55) | TLR2ERN1TLR1TLR6ALDH1A1 | |
| SCHEMBL18106784 | 0.75 | MCHR1 (0.53) | MCHR1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17828378 | 0.74 | MCHR1 (0.35) | TLR2ERN1TLR1TLR6MCHR1 | |
| SCHEMBL8546246 | 0.73 | ALDH1A1 (0.56) | TLR2ERN1TLR1TLR6MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676796-B2 | Tricyclic benzoxaborole compound, preparation method and use thereof | DONG-A ST CO., LTD. (KR) | 2017-06-13 | — | — | US | disclosed |
| US-20160168167-A1 | Tricyclic Benzoxaborole Compound, Preparation Method and Use Thereof | DONG-A ST CO., LTD. (KR) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168167-A1 | Tricyclic Benzoxaborole Compound, Preparation Method and Use Thereof | CYP2C19, CYP2C9, TBCB | TLR2 463/4885ERN1 3767/4885TLR1 185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.