SCHEMBL1782863

SCHEMBL1782863

N#Cc1ccccc1OS(N)(=O)=O

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.47
CA9 Q16790 9/20 0.47
CA1 P00915 8/20 0.47
CA12 O43570 1/20 0.47
GAA P10253 2/20 0.43
POLB P06746 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
STS P08842 1/20 0.42
PKM P14618 1/20 0.41
ALDH1A1 P00352 3/20 0.41
HTT P42858 1/20 0.41
CYP19A1 P11511 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8414710 0.81 GAA (0.47) GAAPOLBSMN1; SMN2PKMALDH1A1
SCHEMBL32689448 0.81 GAA (0.43) GAAPOLBSMN1; SMN2PKMALDH1A1
SCHEMBL19568176 0.81 ELANE (0.53) GAAPOLBSMN1; SMN2PKMALDH1A1
SCHEMBL10084775 0.79 SLC22A12 (0.48) CA2CA9CA1STSCYP19A1
SCHEMBL9451267 0.79 CA2 (0.61) CA2CA9CA1STS
SCHEMBL4443907 0.77 SLC22A12 (0.40) GAAPOLBSMN1; SMN2PKMALDH1A1
SCHEMBL17287453 0.73 ALDH1A1 (0.54) GAAPOLBSMN1; SMN2PKMALDH1A1
SCHEMBL4667728 0.73 STS (0.68) CA2CA9CA1CA12STS
SCHEMBL20458068 0.73 GAA (0.50) GAAPOLBSMN1; SMN2ALDH1A1
SCHEMBL7054403 0.72 GAA (0.64) GAAPOLBSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8173641-B2 4-amino-1,2,3-benzoxathiazine-derivatives as pesticides BAYER CROPSCIENCE AG (DE) 2012-05-08 US claimed
EP-2376465-A1 4-AMINO-1,2,3- BENZOXATHIAZINE DERIVATIVES AS PESTICIDES Bayer CropScience AG (DE) 2011-10-19 EP claimed
US-20110118240-A2 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides BAYER CROPSCIENCE AG (DE) 2011-05-19 US claimed
US-20100267703-A1 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides BAYER CROPSCIENCE AG (DE) 2010-10-21 US claimed
WO-2010072310-A1 4-AMINO-1,2,3- BENZOXATHIAZINE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-07-01 WO claimed
EP-2196461-A1 4-Amino-1,2,3-benzoxathiazine-derivatives as pesticides Bayer CropScience AG (DE) 2010-06-16 EP claimed
US-8173641-B2 4-amino-1,2,3-benzoxathiazine-derivatives as pesticides BAYER CROPSCIENCE AG (DE) 2012-05-08 US disclosed
US-8173641-B2 4-amino-1,2,3-benzoxathiazine-derivatives as pesticides BAYER CROPSCIENCE AG (DE) 2012-05-08 US disclosed
CN-102317271-A 4-Amino-1,2,3-benzoxathiazine-derivatives as pesticides BAYER CROPSCIENCE AG 2012-01-11 CN disclosed
EP-2376465-A1 4-AMINO-1,2,3- BENZOXATHIAZINE DERIVATIVES AS PESTICIDES Bayer CropScience AG (DE) 2011-10-19 EP disclosed
US-20110118240-A2 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides BAYER CROPSCIENCE AG (DE) 2011-05-19 US disclosed
US-20110118240-A2 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides BAYER CROPSCIENCE AG (DE) 2011-05-19 US disclosed
US-20100267703-A1 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides BAYER CROPSCIENCE AG (DE) 2010-10-21 US disclosed
US-20100267703-A1 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides BAYER CROPSCIENCE AG (DE) 2010-10-21 US disclosed
WO-2010072310-A1 4-AMINO-1,2,3- BENZOXATHIAZINE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-07-01 WO disclosed
EP-2196461-A1 4-Amino-1,2,3-benzoxathiazine-derivatives as pesticides Bayer CropScience AG (DE) 2010-06-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267703-A1 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides P2RX5, SLC1A5, P2RX4 CA2 253/4885CA9 3152/4885CA1 713/4885
US-20110118240-A2 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides P2RX5, P2RX4, SLC1A5 CA2 294/4885CA9 3213/4885CA1 701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.