SCHEMBL17829440

SCHEMBL17829440

O=S(=O)(Oc1ccc2ccc(-c3ccc(-c4cc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cc2c1)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
MAOA P21397 2/20 0.39
MAOB P27338 2/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
KMT2A Q03164 7/20 0.38
MEN1 O00255 6/20 0.38
HPGD P15428 6/20 0.38
ALDH1A1 P00352 6/20 0.38
MAPT P10636 5/20 0.38
NTSR1 P30989 1/20 0.38
BRD4 O60885 1/20 0.37
PIK3CD O00329 1/20 0.37
PIK3CA P42336 1/20 0.37
PIK3CB P42338 1/20 0.37
NPSR1 Q6W5P4 3/20 0.37
MAPK1 P28482 2/20 0.37
LMNA P02545 2/20 0.37
TP53 P04637 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17829442 1.00 CA1 (0.43) CA1CA2MAOAMAOBCYP1A1
SCHEMBL17829433 0.95 CA2 (0.44) CA1CA2MAOAMAOBKMT2A
SCHEMBL17829449 0.93 CA2 (0.46) CA1CA2MAOAMAOBKMT2A
SCHEMBL25453605 0.84 CA2 (0.44) CA1CA2MAOAMAOBKMT2A
SCHEMBL17655915 0.83 CA2 (0.42) CA1CA2KMT2AMEN1ALDH1A1
SCHEMBL20622597 0.83 CA2 (0.45) CA1CA2PIK3CDPIK3CAPIK3CB
SCHEMBL25270097 0.81 KMT2A (0.38) CA1CA2MAOAMAOBKMT2A
SCHEMBL31299567 0.80 CA1 (0.53) CA1CA2KMT2AMEN1PIK3CD
SCHEMBL28609675 0.80 CA1 (0.44) CA1CA2MAOAMAOBKMT2A
SCHEMBL19939383 0.80 GPR84 (0.40) CA1CA2MAOAMAOBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160172598-A1 HETERO RING COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2016-06-16 US disclosed
US-20160172598-A1 HETERO RING COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2016-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160172598-A1 HETERO RING COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME CRY1, CRY2, PER2 CA1 4547/4885CA2 4492/4885MAOA 779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.