Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.31 |
| ▸ | CDK1 | P06493 | 3/20 | 0.31 |
| ▸ | CDK4 | P11802 | 3/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.31 |
| ▸ | CCND1 | P24385 | 3/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.31 |
| ▸ | CCND2 | P30279 | 2/20 | 0.31 |
| ▸ | CCND3 | P30281 | 2/20 | 0.31 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14012581 | 0.80 | CDK2 (0.32) | CDK2CCNB2CCNE2CDK1CDK4 | |
| SCHEMBL13268635 | 0.74 | MEN1 (0.41) | CDK2CCNB2CCNE2CDK1CDK4 | |
| SCHEMBL10247712 | 0.72 | CDK2 (0.34) | CDK2CCNE2CDK1CCNE1 | |
| SCHEMBL13884415 | 0.71 | — | — | |
| SCHEMBL17801609 | 0.71 | CDK2 (0.34) | CDK2 | |
| SCHEMBL2619433 | 0.69 | PIK3CG (0.41) | CDK2 | |
| SCHEMBL19825530 | 0.68 | CDK2 (0.43) | CDK2CCNB2CCNE2CDK1CDK4 | |
| SCHEMBL22858887 | 0.68 | CCNB2 (0.31) | CDK2CCNB2CCNE2CDK1CDK4 | |
| SCHEMBL12851783 | 0.67 | CDK2 (0.36) | CDK2CCNB2CCNE2CDK1CDK4 | |
| SCHEMBL12851685 | 0.67 | MAPK1 (0.34) | CDK2CCNB2CCNE2CDK1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11178870-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-11-23 | — | — | US | disclosed |
| US-20200045968-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | MITSUI CHEMICALS AGRO, INC. (JP) | 2020-02-13 | — | — | US | disclosed |
| US-10287279-B2 | Inhibitors of human 12/15-lipoxygenase | THE CHILDREN'S HOSPITAL CORPORATION (US) | 2019-05-14 | — | — | US | disclosed |
| US-20160168137-A1 | INHIBITORS OF HUMAN 12/15-LIPOXYGENASE | THE GENERAL HOSPITAL CORPORATION (US) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11178870-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | PNPO, CYP4X1, PDXK | CDK2 580/4885CCNB2 902/4885CCNE2 996/4885 |
| US-20200045968-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | PNPO, CYP4X1, PDXK | CDK2 580/4885CCNB2 902/4885CCNE2 996/4885 |
| US-10287279-B2 | Inhibitors of human 12/15-lipoxygenase | ALOX15, ALOX12, ALOX15B | CDK2 197/4885CCNB2 577/4885CCNE2 1059/4885 |
| US-20160168137-A1 | INHIBITORS OF HUMAN 12/15-LIPOXYGENASE | ALOX15, ALOX12, ALOX15B | CDK2 197/4885CCNB2 577/4885CCNE2 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.