Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 13/20 | 0.67 |
| ▸ | IDO2 | Q6ZQW0 | 12/20 | 0.67 |
| ▸ | IDO1 | P14902 | 11/20 | 0.67 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17830815 | 0.89 | TDO2 (0.63) | TDO2IDO2IDO1HTR6HTR1A | |
| SCHEMBL17830813 | 0.80 | TDO2 (1.00) | TDO2IDO2IDO1KMT2AMEN1 | |
| SCHEMBL17830822 | 0.77 | TDO2 (0.62) | TDO2IDO2IDO1HTR6HTR1A | |
| SCHEMBL17830805 | 0.77 | TDO2 (0.79) | TDO2IDO2IDO1KMT2AMEN1 | |
| SCHEMBL9106666 | 0.74 | TDO2 (0.63) | TDO2IDO2IDO1KMT2AALDH1A1 | |
| SCHEMBL17830817 | 0.70 | TDO2 (1.00) | TDO2IDO2IDO1HTR6HTR7 | |
| SCHEMBL17830811 | 0.69 | TDO2 (1.00) | TDO2IDO2IDO1KMT2AMEN1 | |
| SCHEMBL28291142 | 0.69 | HTR3E (0.63) | HTR6HTR1AHTR7HTR2BALDH1A1 | |
| SCHEMBL17830807 | 0.69 | TDO2 (0.82) | TDO2IDO2IDO1KMT2AMEN1 | |
| SCHEMBL5864222 | 0.68 | TDO2 (0.55) | TDO2IDO2IDO1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9630969-B2 | N-alkyl tryptanthrin derivative, preparation method for same, and application thereof | SHANGHAI TIN TSZ BIO VALLEY BIOLOGICAL ENGINEERING CO., LTD (CN) | 2017-04-25 | — | — | US | disclosed |
| US-20160168152-A1 | N-ALKYL TRYPTANTHRIN DERIVATIVE, PREPARATION METHOD FOR SAME, AND APPLICATION THEREOF | SHANGHAI TIN TSZ BIO VALLEY BIOLOGICAL ENGINEERING CO., LTD (CN) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168152-A1 | N-ALKYL TRYPTANTHRIN DERIVATIVE, PREPARATION METHOD FOR SAME, AND APPLICATION THEREOF | IDO1, IDO2, TPH1 | TDO2 9/4885IDO2 2/4885IDO1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.