Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.63 |
| ▸ | HTR3B | O95264 | 4/20 | 0.63 |
| ▸ | HTR3A | P46098 | 4/20 | 0.63 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.63 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.63 |
| ▸ | HTR5A | P47898 | 3/20 | 0.63 |
| ▸ | HTR1A | P08908 | 6/20 | 0.51 |
| ▸ | HTR7 | P34969 | 5/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.50 |
| ▸ | HTR6 | P50406 | 3/20 | 0.50 |
| ▸ | HTR1D | P28221 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | HTR1B | P28222 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138664 | 0.78 | HTR3A (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL30870394 | 0.78 | HTR3A (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5252903 | 0.76 | HTR5A (0.68) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL15708159 | 0.76 | HTR3A (0.96) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL29688470 | 0.76 | HTR3A (0.96) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6776973 | 0.76 | HTR5A (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL478208 | 0.75 | ADRB1 (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL5249558 | 0.75 | HTR5A (0.67) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL15707949 | 0.75 | HTR3E (0.69) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5366654 | 0.74 | HTR6 (0.63) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191854-B | Fluoro- 7- piperazine-nalidixic acid compound of 1- (N- Ciprofloxacin amide groups) -6- and its preparation method and application | 河南大学 | 2019-05-24 | — | — | CN | disclosed |
| CN-108047220-B | Fluoro- 7- piperazine-nalidixic acid compound of 1- (N- fleraxacin amide groups) -6- and its preparation method and application | 河南大学 | 2019-05-24 | — | — | CN | disclosed |