Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.54 |
| ▸ | ESRRB | O95718 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 4/20 | 0.39 |
| ▸ | ACE | P12821 | 4/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834012 | 0.82 | ELANE (0.46) | ELANEESRRBSMN1; SMN2MEN1NPC1 | |
| SCHEMBL19862709 | 0.82 | ELANE (0.61) | ELANESMN1; SMN2MEN1KMT2A | |
| SCHEMBL9888810 | 0.80 | ELANE (0.43) | ELANEMEN1NPC1KMT2A | |
| SCHEMBL17834011 | 0.79 | ELANE (0.43) | ELANEESRRBPTGS2PRSS1TMPRSS15 | |
| SCHEMBL2292808 | 0.77 | ELANE (0.45) | ELANEMEN1NPC1KMT2A | |
| SCHEMBL19862712 | 0.77 | ELANE (0.54) | ELANESMN1; SMN2PPARAMEN1KMT2A | |
| SCHEMBL12393844 | 0.76 | MAPT (0.47) | ELANEMMEACESMN1; SMN2MEN1 | |
| SCHEMBL19862711 | 0.76 | ELANE (0.53) | ELANEPTGS2SMN1; SMN2PPARGPPARA | |
| SCHEMBL27878297 | 0.76 | LMNA (0.47) | ELANESMN1; SMN2NPC1 | |
| SCHEMBL17834013 | 0.75 | ELANE (0.41) | ELANEESRRBSMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160169920-A1 | ION SENSOR | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160169920-A1 | ION SENSOR | ORAI1, CACNA1E, NCS1 | ELANE 3815/4885ESRRB 2830/4885PTGS2 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.