Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.43 |
| ▸ | ESRRB | O95718 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834012 | 0.79 | ELANE (0.46) | ELANEESRRBKDM4EESR1MEN1 | |
| SCHEMBL17834010 | 0.79 | ELANE (0.54) | ELANEESRRBPRSS1TMPRSS15EPHX2 | |
| SCHEMBL17834013 | 0.74 | ELANE (0.41) | ELANEESRRBKDM4EGAAXBP1 | |
| SCHEMBL825544 | 0.71 | ELANE (0.71) | ELANEGAAL3MBTL1MEN1NPC1 | |
| SCHEMBL19680357 | 0.70 | TDP1 (0.49) | KDM4ENPSR1MEN1NPC1KMT2A | |
| SCHEMBL12032774 | 0.70 | TDP1 (0.49) | KDM4ENPSR1MEN1NPC1KMT2A | |
| SCHEMBL19862709 | 0.69 | ELANE (0.61) | ELANEGAAL3MBTL1MEN1KMT2A | |
| SCHEMBL10050637 | 0.69 | L3MBTL1 (0.59) | ELANEPPARGPPARAGAAL3MBTL1 | |
| SCHEMBL12455656 | 0.69 | PKM (0.50) | PPARAGAANPSR1L3MBTL1MEN1 | |
| SCHEMBL25501774 | 0.68 | RARB (0.53) | KDM4EPRSS1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160169920-A1 | ION SENSOR | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160169920-A1 | ION SENSOR | ORAI1, CACNA1E, NCS1 | ELANE 3815/4885ESRRB 2830/4885KDM4E 1995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.